AR-R17779

AR-R17779，分子式C9H14N2O2，是α7菸鹼型乙醯膽鹼受體的完全激动剂[1][2]。

AR-R17779
IUPAC名
(2S)-4′-Azaspiro[bicyclo[2.2.2]octane-2,5′-[1,3]oxazolidin]-2′-one
别名 (−)-Spiro[1-azabicyclo[2.2.2]octane-3,5′-oxazolidin-2′-one]
识别
CAS号 178419-47-1  checkY
PubChem 5310971
ChemSpider 4470515
SMILES
 
  • O=C3O[C@]1(CN2CCC1CC2)CN3
InChI
 
  • 1/C9H14N2O2/c12-8-10-5-9(13-8)6-11-3-1-7(9)2-4-11/h7H,1-6H2,(H,10,12)/t9-/m0/s1
ChEBI CHEBI:420311
性质
化学式 C9H14N2O2
摩尔质量 182.22 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

参考文献
  1. Mullen, G.; Napier, A.; Balestra, M.; Decory, T.; Hale, G.; Macor, J.; Mack, R.; Loch, J.; Wu, E.; Kover, A.; Verhoest, P.; Sampognaro, A.; Phillips, E.; Zhu, Y.; Murray, R.; Griffith, R.; Blosser, J.; Gurley, D.; Machulskis, A.; Zongrone, J.; Rosen, A.; Gordon, J. . Journal of Medicinal Chemistry. 2000, 43 (22): 4045–4050. PMID 11063601. doi:10.1021/jm000249r.
  2. Macor, J.; Mullen, G.; Verhoest, P.; Sampognaro, A.; Shepardson, B.; Mack, R. . The Journal of Organic Chemistry. 2004, 69 (19): 6493–6495. PMID 15357617. doi:10.1021/jo049404q.
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