伐地美生

伐地美生（INN：英語：，开发代号：ASA404[1]），也叫5,6-二甲基吨酮-4-乙酸（dimethylxanthone acetic acid，缩写DMXAA）、2,5-己酮可可碱等，是一种有机化合物，分子式C17H14O4，可作为肿瘤血管破坏剂（tumor-VDA）[2]。

伐地美生
臨床資料
其他名稱ASA404, DMXAA
ATC碼
  • 未分配
识别
  • (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)-acetic acid
CAS号117570-53-3  checkY
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.107.097
化学
化学式C17H14O4
摩尔质量282.30 g·mol−1
3D模型（JSmol）
  • CC1=C(OC(C(CC(O)=O)=CC=C3)=C3C2=O)C2=CC=C1C
  • InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19) ☒N
  • Key:XGOYIMQSIKSOBS-UHFFFAOYSA-N ☒N

参考文献
  1. . The New Zealand Herald. 14 February 2009 [2009-02-13]. （原始内容存档于2016-03-03）.
  2. ASA404, A Novel Cancer Agent, Begins Pivotal Trial To Explore New Approach In Treating Lung Cancer, The Leading Cause Of Cancer Death （页面存档备份，存于）, Medical News Today, 14 April 2008
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