CCL1
CCL1（英語：）是一小分子的细胞因子属于CC趋化因子家族，是由活化的T细胞分泌的糖蛋白[1]。CCL1与细胞表面的趋化因子受体CCR8结合[2]。CCL1对单核细胞，自然杀伤细胞，未成熟的B细胞和树突状细胞有细胞趋化作用[1]。人类的CCL1基因与许多CC趋化因子的基因相邻聚集在第17染色体上[3].
| 趋化因子（C-C基序）配体1 | |
|---|---|
| 識別 | |
| 符號 | CCL1 |
| 替換符號 | SCYA1, I-309, TCA3, P500, SISe |
| Entrez | 6346 |
| HUGO | 10609 |
| OMIM | 182281 |
| PDB | 1EL0 |
| RefSeq | NM_002981 |
| UniProt | P22362 |
| 其他資料 | |
| 基因座 | 17 q11.2 |
参见
- 趋化因子
- CCR8
参考文献
- Miller MD, Krangel MS. The human cytokine I-309 is a monocyte chemoattractant. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2950-4.
- Roos RS, Loetscher M, Legler DF, Clark-Lewis I, Baggiolini M, Moser B. Identification of CCR8, the receptor for the human CC chemokine I-309. J Biol Chem. 1997 Jul 11;272(28):17251-4.
- Miller MD, Wilson SD, Dorf ME, Seuanez HN, O'Brien SJ, Krangel MS. Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines. J Immunol. 1990 Oct 15;145(8):2737-44.
外部链接
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