HSG4112

Vutiglabridin(中文译名未知),开发代号HSG4112,是一种外消旋的有机化合物,化学式为C22H26O4,为实验性抗肥胖药物,是光甘草定的结构类似物。[1][2][3]

HSG4112
法律規範狀態
法律規範
  • Investigational
识别
  • 2-(8,8-Dimethyl-3,4,9,10-tetrahydro-2H-pyrano[2,3-h]chromen-3-yl)-5-ethoxyphenol
CAS号1800188-47-9  checkY
PubChem CID
UNII
化学
化学式C22H26O4
摩尔质量354.45 g·mol−1
3D模型(JSmol
  • OC1=CC(OCC)=CC=C1C2COC=3C(=CC=C4OC(C)(C)CCC43)C2

它可以5-羟基-2,2-二甲基-2H-1-苯并呋喃-6-甲醛为原料经多步反应制得。[4]

参考文献

  1. Hyeon, Jooseung; Lee, Jihan; Kim, Eunju; Lee, Hyeong Min; Kim, Kwang Pyo; Shin, Jaejin; Park, Hyung Soon; Lee, Yun-Il; Nam, Chang-Hoon. . Experimental Gerontology. October 2023, 181: 112269. doi:10.1016/j.exger.2023.112269可免费查阅.
  2. Na, Joo Young; Yoon, Deok Yong; Yoo, Hyounggyoon; Lee, SeungHwan; Yu, Kyung‐Sang; Jang, In‐Jin; Yoo, Sang‐Ku; Kim, Youngah; Oh, Jaeseong. . Clinical and Translational Science. November 2022, 15 (11): 2744–2757. ISSN 1752-8054. PMC 9652434可免费查阅. doi:10.1111/cts.13401 (英语).
  3. Choi, Leo Sungwong; Jo, In Geun; Kang, Ku Suk; Im, Jeong Ho; Kim, Jiyoung; Kim, Jinyoung; Chung, Jin Wook; Yoo, Sang-Ku. . International Journal of Obesity. January 2021, 45 (1): 130–142. ISSN 1476-5497. doi:10.1038/s41366-020-00686-1可免费查阅 (英语).
  4. Yoo, Sang Ku; Chung, Jin Wook; Jo, In Geun; Im, Jeong Ho; Kang, Ku Suk; Kim, Jin Young. Pyranochromenyl-phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease. 2015. WO2015099392() / 2014. CN105849111A(中文) / 2016. US2016272650A1(英文).
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