HSG4112
Vutiglabridin(中文译名未知),开发代号HSG4112,是一种外消旋的有机化合物,化学式为C22H26O4,为实验性抗肥胖药物,是光甘草定的结构类似物。[1][2][3]
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CAS号 | 1800188-47-9 |
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化学式 | C22H26O4 |
摩尔质量 | 354.45 g·mol−1 |
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它可以5-羟基-2,2-二甲基-2H-1-苯并呋喃-6-甲醛为原料经多步反应制得。[4]
参考文献
- Hyeon, Jooseung; Lee, Jihan; Kim, Eunju; Lee, Hyeong Min; Kim, Kwang Pyo; Shin, Jaejin; Park, Hyung Soon; Lee, Yun-Il; Nam, Chang-Hoon. . Experimental Gerontology. October 2023, 181: 112269. doi:10.1016/j.exger.2023.112269 .
- Na, Joo Young; Yoon, Deok Yong; Yoo, Hyounggyoon; Lee, SeungHwan; Yu, Kyung‐Sang; Jang, In‐Jin; Yoo, Sang‐Ku; Kim, Youngah; Oh, Jaeseong. . Clinical and Translational Science. November 2022, 15 (11): 2744–2757. ISSN 1752-8054. PMC 9652434 . doi:10.1111/cts.13401 (英语).
- Choi, Leo Sungwong; Jo, In Geun; Kang, Ku Suk; Im, Jeong Ho; Kim, Jiyoung; Kim, Jinyoung; Chung, Jin Wook; Yoo, Sang-Ku. . International Journal of Obesity. January 2021, 45 (1): 130–142. ISSN 1476-5497. doi:10.1038/s41366-020-00686-1 (英语).
- Yoo, Sang Ku; Chung, Jin Wook; Jo, In Geun; Im, Jeong Ho; Kang, Ku Suk; Kim, Jin Young. Pyranochromenyl-phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease. 2015. WO2015099392() / 2014. CN105849111A(中文) / 2016. US2016272650A1(英文).
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