ICBP43

ICBP43是43种人类乳腺癌细胞系的列表[1]，由美国国家癌症研究所的“癌症生物学综合计划”（Integrative Cancer Biology Program）列出[2]，用于药物筛选等许多生物医学研究[3]。

细胞系

三阴性乳腺癌

细胞系	倍增时间	转录亚型	ATCC ID	文献	外部链接
BT-20	66.15h	Basal	HTB-19	[4]	CVCL_0178
MDA-MB-231	41.9h	Claudin-low	HTB-26	[5]	CVCL_0062
MDA-MB-468	62h	Basal	HTB-132	[6]	CVCL_0419
Hs 578T	53.8h	Claudin-low	HTB-126	[7]	CVCL_0332
BT-549	53.9h	Claudin-low	HTB-122	[8]	CVCL_1092
184B5	56.15h	Basal	CRL-8799	[9]	CVCL_4688
DU4475	90h	？	HTB-123	[10]	CVCL_1183
HCC38	50.98h	Claudin-low	CRL-2314	[11]	CVCL_1267
HCC70	67.80h	Basal	CRL-2315	[11]	CVCL_1270
HCC1187	69.35h	Basal	CRL-2322	[11]	CVCL_1247
HCC1395	84.07h	Claudin-low	CRL-2324	[11]	CVCL_1349
HCC1599	4-5d	Basal	CRL-2331	[11]	CVCL_1256
HCC1806	36.66h	Basal	CRL-2335	[11]	CVCL_1258
HCC1937	53.49h	Basal	CRL-2336	[11]	CVCL_0290
HCC2157	？	？	CRL-2340	[11]	CVCL_1261
MDA-MB-157	66.98h	Claudin-low	HTB-24	[6]	CVCL_0618
MDA-MB-436	89.31h	Claudin-low	HTB-130	[6]	CVCL_0623
MDA-MB-453	62.49h	Luminal	HTB-131	[12]	CVCL_0418

HR+

细胞系	倍增时间	转录亚型	ATCC ID	文献	外部链接
MCF-7	25.4h	Luminal	HTB-22	[13]	CVCL_0031
T-47D	45.5h	Luminal	HTB-133	[14]	CVCL_0553
BT-483	140.00h	Luminal	HTB-121	[15]	CVCL_2319
CAMA-1	72.94h	Luminal	HTB-21	[16]	CVCL_1115
HCC1428	88.48h	Luminal	CRL-2327	[11]	CVCL_1252
HCC1500	46.85h	？	CRL-2329	[11]	CVCL_1254
MDA-MB-134-VI	82.67h	Luminal	HTB-23	[6]	CVCL_0617
MDA-MB-175-VII	112.26h	Luminal	HTB-25	[6]	CVCL_1400
MDA-MB-415	88.87h	Luminal	HTB-128	[6]	CVCL_0621
ZR-75-1	70.09h	Luminal	CRL-1504	[17]	CVCL_0588

HER2amp

细胞系	倍增时间	转录亚型	ATCC ID	文献	外部链接
SK-BR-3	56.19h	HER2+	HTB-30	[18]	CVCL_0033
AU565	46.31h	HER2+	CRL-2351	[19]	CVCL_1074
BT-474	92.49h	HER2+	HTB-20	[20]	CVCL_0179
HCC202	212.49h	HER2+	CRL-2316	[11]	CVCL_2062
HCC1419	161.42h	HER2+	CRL-2326	[11]	CVCL_1251
HCC1569	45.43h	？	CRL-2330	[11]	CVCL_1255
HCC1954	43.81h	HER2+	CRL-2338	[11]	CVCL_1259
HCC2218	120h	HER2+	CRL-2343	[11]	CVCL_1263
MDA-MB-361	92.83h	HER2+	HTB-27	[6]	CVCL_0620
UACC-812	104.68h	HER2+	CRL-1897	[21]	CVCL_1782
UACC-893	248.53h	Luminal	CRL-1902	[21]	CVCL_1781
ZR-75-30	324.46h	Luminal	CRL-1504	[22]	CVCL_1661

NM

细胞系	倍增时间	转录亚型	ATCC ID	文献	外部链接
MCF-10A	26.74h	Non-malignant Basal	CRL-10317	[23]	CVCL_0598
MCF-10F	47.44h	Non-malignant Basal	CRL-10318	[23]	CVCL_3633
MCF-12A	35.42h	Non-malignant Basal	CRL-10782	[24]	CVCL_3744

另见

NCI-60，国家癌症研究所（NCI）列出的60种人类癌细胞系列表
LL-100，100种人类淋巴瘤（Lymphoma）与白血病（Leukemia）细胞系的列表

参考文献

. lincs.hms.harvard.edu.
. lincs.hms.harvard.edu.
Anderson, Alexander R. A.; Tomlin, Claire J.; Couch, Jennifer; Gallahan, Dan. . Interface Focus. 2013-08-06, 3 (4): 20130023. doi:10.1098/RSFS.2013.0023.
Chavez, KJ; Garimella, SV; Lipkowitz, S. . Breast disease. 2010, 32 (1-2): 35–48 [2019-12-04]. PMID 21778573. doi:10.3233/BD-2010-0307.
Cailleau, R; Young, R; Olivé, M; Reeves WJ, Jr. . Journal of the National Cancer Institute. 1974-09, 53 (3): 661–74. PMID 4412247. doi:10.1093/jnci/53.3.661.
Cailleau, R; Olivé, M; Cruciger, QV. . In vitro. 1978-11, 14 (11): 911–5 [2020-02-14]. PMID 730202. doi:10.1007/bf02616120. （原始内容存档于2020-02-14）.
Hackett, AJ; Smith, HS; Springer, EL; Owens, RB; Nelson-Rees, WA; Riggs, JL; Gardner, MB. . Journal of the National Cancer Institute. 1977-06, 58 (6): 1795–806. PMID 864756. doi:10.1093/jnci/58.6.1795.
Lasfargues, EY; Coutinho, WG; Redfield, ES. . Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）.
Stampfer, MR; Bartley, JC. . Proceedings of the National Academy of Sciences of the United States of America. 1985-04, 82 (8): 2394–8. PMID 3857588. doi:10.1073/pnas.82.8.2394.
Langlois, AJ; Holder WD, Jr; Iglehart, JD; Nelson-Rees, WA; Wells SA, Jr; Bolognesi, DP. . Cancer research. 1979-07, 39 (7 Pt 1): 2604–13. PMID 221108.
Gazdar, AF; Kurvari, V; Virmani, A; Gollahon, L; Sakaguchi, M; Westerfield, M; Kodagoda, D; Stasny, V; Cunningham, HT; Wistuba, II; Tomlinson, G; Tonk, V; Ashfaq, R; Leitch, AM; Minna, JD; Shay, JW. . International journal of cancer. 1998-12-09, 78 (6): 766–74. PMID 9833771. doi:10.1002/(sici)1097-0215(19981209)78:6<766::aid-ijc15>3.0.co;2-l.
Hall, RE; Birrell, SN; Tilley, WD; Sutherland, RL. . European journal of cancer (Oxford, England : 1990). 1994, 30A (4): 484–90 [2020-02-14]. PMID 8018407. doi:10.1016/0959-8049(94)90424-3.
Lee, Adrian V.; et al. . Journal of the National Cancer Institute. 1 July 2015, 107 (7): djv073. PMID 25828948. doi:10.1093/jnci/djv073.
Yu, S; Kim, T; Yoo, KH; Kang, K. . Biochemical and biophysical research communications. 2017-05-06, 486 (3): 752–758 [2019-11-30]. PMID 28342866. doi:10.1016/j.bbrc.2017.03.114.
Lasfargues, EY; Coutinho, WG; Redfield, ES. . Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）.
Kerbel, RS; Pross, HF; Leibovitz, A. . International journal of cancer. 1977-11-15, 20 (5): 673–9. PMID 924690. doi:10.1002/ijc.2910200505.
Dorssers, LC; van Agthoven, T. . Pathology, research and practice. 1996-07, 192 (7): 743–51 [2019-11-28]. PMID 8880875. doi:10.1016/S0344-0338(96)80096-3.
. Memorial Sloan-Kettering Cancer Center. [2018-06-18]. （原始内容存档于2018-06-18）.
Bacus, SS; Kiguchi, K; Chin, D; King, CR; Huberman, E. . Molecular carcinogenesis. 1990, 3 (6): 350–62 [2019-12-04]. PMID 1980588. doi:10.1002/mc.2940030607.
Lasfargues, EY; Coutinho, WG; Dion, AS. . In vitro. 1979-09, 15 (9): 723–9 [2019-12-07]. PMID 94035. doi:10.1007/bf02618252.
Meltzer, P; Leibovitz, A; Dalton, W; Villar, H; Kute, T; Davis, J; Nagle, R; Trent, J. . British journal of cancer. 1991-05, 63 (5): 727–35. PMID 1674877. doi:10.1038/bjc.1991.164.
Engel, LW; Young, NA; Tralka, TS; Lippman, ME; O'Brien, SJ; Joyce, MJ. . Cancer research. 1978-10, 38 (10): 3352–64. PMID 688225.
Soule, HD; Maloney, TM; Wolman, SR; Peterson WD, Jr; Brenz, R; McGrath, CM; Russo, J; Pauley, RJ; Jones, RF; Brooks, SC. . Cancer research. 1990-09-15, 50 (18): 6075–86. PMID 1975513.
Neve, RM; Chin, K; Fridlyand, J; Yeh, J; Baehner, FL; Fevr, T; Clark, L; Bayani, N; Coppe, JP; Tong, F; Speed, T; Spellman, PT; DeVries, S; Lapuk, A; Wang, NJ; Kuo, WL; Stilwell, JL; Pinkel, D; Albertson, DG; Waldman, FM; McCormick, F; Dickson, RB; Johnson, MD; Lippman, M; Ethier, S; Gazdar, A; Gray, JW. . Cancer cell. 2006-12, 10 (6): 515–27. PMID 17157791. doi:10.1016/j.ccr.2006.10.008.

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[1] . lincs.hms.harvard.edu.

[2] . lincs.hms.harvard.edu.

[3] Anderson, Alexander R. A.; Tomlin, Claire J.; Couch, Jennifer; Gallahan, Dan. . Interface Focus. 2013-08-06, 3 (4): 20130023. doi:10.1098/RSFS.2013.0023.

[4] Chavez, KJ; Garimella, SV; Lipkowitz, S. . Breast disease. 2010, 32 (1-2): 35–48 [2019-12-04]. PMID 21778573. doi:10.3233/BD-2010-0307.

[5] Cailleau, R; Young, R; Olivé, M; Reeves WJ, Jr. . Journal of the National Cancer Institute. 1974-09, 53 (3): 661–74. PMID 4412247. doi:10.1093/jnci/53.3.661.

[MDA-MB-6] Cailleau, R; Olivé, M; Cruciger, QV. . In vitro. 1978-11, 14 (11): 911–5 [2020-02-14]. PMID 730202. doi:10.1007/bf02616120. （原始内容存档于2020-02-14）.

[578T-7] Hackett, AJ; Smith, HS; Springer, EL; Owens, RB; Nelson-Rees, WA; Riggs, JL; Gardner, MB. . Journal of the National Cancer Institute. 1977-06, 58 (6): 1795–806. PMID 864756. doi:10.1093/jnci/58.6.1795.

[aa-8] Lasfargues, EY; Coutinho, WG; Redfield, ES. . Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）.

[184B5-9] Stampfer, MR; Bartley, JC. . Proceedings of the National Academy of Sciences of the United States of America. 1985-04, 82 (8): 2394–8. PMID 3857588. doi:10.1073/pnas.82.8.2394.

[10] Langlois, AJ; Holder WD, Jr; Iglehart, JD; Nelson-Rees, WA; Wells SA, Jr; Bolognesi, DP. . Cancer research. 1979-07, 39 (7 Pt 1): 2604–13. PMID 221108.

[HCC-11] Gazdar, AF; Kurvari, V; Virmani, A; Gollahon, L; Sakaguchi, M; Westerfield, M; Kodagoda, D; Stasny, V; Cunningham, HT; Wistuba, II; Tomlinson, G; Tonk, V; Ashfaq, R; Leitch, AM; Minna, JD; Shay, JW. . International journal of cancer. 1998-12-09, 78 (6): 766–74. PMID 9833771. doi:10.1002/(sici)1097-0215(19981209)78:6<766::aid-ijc15>3.0.co;2-l.

[Hall-12] Hall, RE; Birrell, SN; Tilley, WD; Sutherland, RL. . European journal of cancer (Oxford, England : 1990). 1994, 30A (4): 484–90 [2020-02-14]. PMID 8018407. doi:10.1016/0959-8049(94)90424-3.

[13] Lee, Adrian V.; et al. . Journal of the National Cancer Institute. 1 July 2015, 107 (7): djv073. PMID 25828948. doi:10.1093/jnci/djv073.

[14] Yu, S; Kim, T; Yoo, KH; Kang, K. . Biochemical and biophysical research communications. 2017-05-06, 486 (3): 752–758 [2019-11-30]. PMID 28342866. doi:10.1016/j.bbrc.2017.03.114.

[15] Lasfargues, EY; Coutinho, WG; Redfield, ES. . Journal of the National Cancer Institute. 1978-10, 61 (4): 967–78 [2019-12-07]. PMID 212572. （原始内容存档于2013-12-17）.

[16] Kerbel, RS; Pross, HF; Leibovitz, A. . International journal of cancer. 1977-11-15, 20 (5): 673–9. PMID 924690. doi:10.1002/ijc.2910200505.

[#1-17] Dorssers, LC; van Agthoven, T. . Pathology, research and practice. 1996-07, 192 (7): 743–51 [2019-11-28]. PMID 8880875. doi:10.1016/S0344-0338(96)80096-3.

[MSKCC-18] . Memorial Sloan-Kettering Cancer Center. [2018-06-18]. （原始内容存档于2018-06-18）.

[AU-565-19] Bacus, SS; Kiguchi, K; Chin, D; King, CR; Huberman, E. . Molecular carcinogenesis. 1990, 3 (6): 350–62 [2019-12-04]. PMID 1980588. doi:10.1002/mc.2940030607.

[20] Lasfargues, EY; Coutinho, WG; Dion, AS. . In vitro. 1979-09, 15 (9): 723–9 [2019-12-07]. PMID 94035. doi:10.1007/bf02618252.

[UACC-21] Meltzer, P; Leibovitz, A; Dalton, W; Villar, H; Kute, T; Davis, J; Nagle, R; Trent, J. . British journal of cancer. 1991-05, 63 (5): 727–35. PMID 1674877. doi:10.1038/bjc.1991.164.

[22] Engel, LW; Young, NA; Tralka, TS; Lippman, ME; O'Brien, SJ; Joyce, MJ. . Cancer research. 1978-10, 38 (10): 3352–64. PMID 688225.

[MCF-10-23] Soule, HD; Maloney, TM; Wolman, SR; Peterson WD, Jr; Brenz, R; McGrath, CM; Russo, J; Pauley, RJ; Jones, RF; Brooks, SC. . Cancer research. 1990-09-15, 50 (18): 6075–86. PMID 1975513.

[24] Neve, RM; Chin, K; Fridlyand, J; Yeh, J; Baehner, FL; Fevr, T; Clark, L; Bayani, N; Coppe, JP; Tong, F; Speed, T; Spellman, PT; DeVries, S; Lapuk, A; Wang, NJ; Kuo, WL; Stilwell, JL; Pinkel, D; Albertson, DG; Waldman, FM; McCormick, F; Dickson, RB; Johnson, MD; Lippman, M; Ethier, S; Gazdar, A; Gray, JW. . Cancer cell. 2006-12, 10 (6): 515–27. PMID 17157791. doi:10.1016/j.ccr.2006.10.008.