NCI-60

NCI-60是美国国家癌症研究所(National Cancer Institute,NCI)列出的60种人类癌症细胞系的列表[1],用于抗癌药物筛选等科学研究[2]

细胞系

白血病

细胞系类型性别倍增时间文献外部链接
CCRF-CEM急性淋巴性白血病26.7h[3]CVCL_0207
HL-60急性早幼粒细胞白血病28.6h[4]CVCL_0002
K-562慢性髓细胞性白血病19.6h[5][6]CVCL_0004
MOLT-4急性淋巴性白血病27.9h[7]CVCL_0013
RPMI-8226多發性骨髓瘤33.5h[8]CVCL_0014
SR-786间变性大细胞淋巴瘤28.7h[9]CVCL_1711

非小细胞肺癌

细胞系性别倍增时间文献外部链接
A54922.9h[10]CVCL_0023
EKVX43.6h[11]CVCL_1195
HOP-6239h[12]CVCL_1285
HOP-9279.5h[13]CVCL_1286
NCI-H22661h[14]CVCL_1544
NCI-H2333.4h[14]CVCL_1547
NCI-H322M35.3h[14]CVCL_1557
NCI-H46017.8h[14]CVCL_0459
NCI-H52238.2h[14]CVCL_1567

结直肠癌

细胞系性别倍增时间文献外部链接
COLO 20523.8h[15]CVCL_0218
HCC2998未知31.5h[14]CVCL_1266
HCT 11617.4h[16]CVCL_0291
HCT 1520.6h[17]CVCL_0292
HT-2919.5h[18]CVCL_0320
KM1223.7h[13]CVCL_1331
SW62020.4h[19]CVCL_0547

中枢神经系统

细胞系性别倍增时间文献外部链接
SF-26833.1h[20]CVCL_1689
SF-29529.5h[14]CVCL_1690
SF-53935.4h[14]CVCL_1691
SNB-1934.6h[21]CVCL_0535
SNB-7562.8h[21]CVCL_1706
U-251MG23.8h[22]CVCL_0021

黑色素瘤

细胞系性别倍增时间文献外部链接
LOX-IMVI20.5h[23]CVCL_1381
Malme-3M46.2h[24]CVCL_1438
M1426.3h[25]CVCL_1395
SK-MEL-245.5h[26]CVCL_0069
SK-MEL-2835.1h[26]CVCL_0526
SK-MEL-525.2h[26]CVCL_0527
UACC-257未知38.5h[13]CVCL_1779
UACC-62未知31.3h[13]CVCL_1780

卵巢癌

细胞系倍增时间文献外部链接
IGROV-131h[27]CVCL_1304
OVCAR-334.7h[28]CVCL_0465
OVCAR-441.4h[28]CVCL_1627
OVCAR-548.8h[28]CVCL_1628
OVCAR-826.1h[28]CVCL_1629
SK-OV-348.7h[29]CVCL_0532

肾癌

细胞系性别倍增时间文献外部链接
786-O22.4h[30]CVCL_1051
A-49866.8h[31]CVCL_1056
ACHN27.5h[32]CVCL_1067
CAKI-139h[33]CVCL_0234
RXF 39362.9h[13]CVCL_1673
SN12C29.5h[34]CVCL_1705
TK-1051.3h[35]CVCL_1773
UO-3141.7h[14]CVCL_1911

前列腺癌

细胞系性别倍增时间文献外部链接
PC-327.1h[36]CVCL_0035
DU14532.3h[37]CVCL_0105

乳腺癌

细胞系类型倍增时间文献外部链接
MCF-7HR+25.4h[38]CVCL_0031
MDA-MB-231三陰性乳癌41.9h[39]CVCL_0062
MDA-MB-468三陰性乳癌62h[40]CVCL_0419
Hs 578T三陰性乳癌53.8h[41]CVCL_0332
BT-549三陰性乳癌53.9h[42]CVCL_1092
T-47DHR+45.5h[43]CVCL_0553

额外细胞系

细胞系类型来源文献外部链接
LXFL 529非小细胞肺癌人类[13]CVCL_D085
DMS 114小细胞肺癌人类男性[44]CVCL_1174
SHP-77小细胞肺癌人类男性[45]CVCL_1693
DLD-1结直肠癌人类男性[46]CVCL_0248
KM20L2结直肠癌人类女性[47]CVCL_D889
SNB-78腦瘤人类男性[21]CVCL_B321
XF 498腦瘤人类[13]CVCL_8928
RPMI-7951黑色素瘤人类女性[48]CVCL_1666
M19-MEL黑色素瘤人类[13]CVCL_B415
RXF-631L腎癌人类[13]CVCL_A780
SN12K1腎癌人类男性[34]CVCL_D106
P388白血病雌性小鼠[49]CVCL_7222
P388/ADR白血病雌性小鼠[14]CVCL_IZ75

另见

  • LL-100,100种人类淋巴瘤Lymphoma)与白血病Leukemia)细胞系的列表
  • ICBP43,NCI的“癌症生物学综合计划”(Integrative Cancer Biology Program)列出的43种人类乳腺癌细胞系列表
  • JFCR39,日本癌研究會Japanese Foundation for Cancer Research)列出的39种人类细胞系的列表

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