ORG-26576

ORG-26576是一种有机化合物，分子式C11H12N2O2，最初由RespireRx公司（原称Cortex Pharmaceuticals公司）的科学家研发，后交由欧加农公司继续开发，能有效增强AMPA受体功能，促进脑源性神经营养因子释放[1][2][3]。

ORG-26576
识别
  • (7S)-9-oxa-3,11-diazatricyclo[8.4.0.03,7]tetradeca-1(10),11,13-trien-2-one
CAS号1026791-61-6
PubChem CID
ChemSpider
UNII
化学
化学式C11H12N2O2
摩尔质量204.23 g·mol−1
3D模型（JSmol）
  • C1C[C@H]2COC3=C(C=CC=N3)C(=O)N2C1
  • InChI=1S/C11H12N2O2/c14-11-9-4-1-5-12-10(9)15-7-8-3-2-6-13(8)11/h1,4-5,8H,2-3,6-7H2/t8-/m0/s1
  • Key:FIKUEZUFASUKAH-QMMMGPOBSA-N

参考文献
  1. Jordan GR, McCulloch J, Shahid M, Hill DR, Henry B, Horsburgh K. . Neuropharmacology. August 2005, 49 (2): 254–64. PMID 15993447. S2CID 24805124. doi:10.1016/j.neuropharm.2005.03.011.
  2. Su XW, Li XY, Banasr M, Koo JW, Shahid M, Henry B, Duman RS. . Psychopharmacology. October 2009, 206 (2): 215–22. PMID 19603152. S2CID 19408716. doi:10.1007/s00213-009-1598-0.
  3. Hamlyn E, Brand L, Shahid M, Harvey BH. . Behavioural Pharmacology. October 2009, 20 (7): 662–7. PMID 19741506. S2CID 27814943. doi:10.1097/FBP.0b013e328331ba1b.
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