SOX基因家族

SOX基因家族英語:,即SRY相关HMG盒基因家族,)是一类高速泳动族转录因子[1]

SOXB subfamily, C-terminal next to HMG box
鑑定
標誌SOXp
PfamPF12336旧版
InterProIPR022097
SOXE, N-terminal
鑑定
標誌Sox_N
PfamPF12444旧版
InterProIPR022151
SOXF, C-terminal, 9aaTAD
鑑定
標誌SOX_C
InterProIPR021934
PROSITEPS51516
SOXF, central
鑑定
標誌Sox17_18_mid
PfamPF12067旧版
InterProIPR033392

人类基因组拥有SRY等20个SOX家族成员,如下[2]

  • SoxA: SRY
  • SoxB1: SOX1, Sox2, SOX3
  • SoxB2: SOX14, SOX21
  • SoxC: SOX4, SOX11, SOX12
  • SoxD: SOX5, SOX6, SOX13
  • SoxE: SOX8, SOX9, SOX10
  • SoxF: SOX7, SOX17, SOX18
  • SoxG: SOX15
  • SoxH: SOX30

参考文献

  1. Bowles, J; Schepers G; Koopman P. . Dev. Biol. November 2000, 227 (2): 239–55. PMID 11071752. doi:10.1006/dbio.2000.9883可免费查阅.
  2. Guth SI, Wegner M. . Cell. Mol. Life Sci. October 2008, 65 (19): 3000–18. PMID 18516494. S2CID 8943181. doi:10.1007/s00018-008-8138-7.

外部链接

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