TATA结合蛋白

TATA结合蛋白质（英語：，TBP）是一种通用转录因子，具体结合于DNA序列上的TATA盒。TATA盒位于真核基因的转录起始位点上游约25个bp，属于啟動子区[6]。TBP可以和各个TBP相关因子共同组成通用转录因子TFIID,再进一步组成RNA聚合酶Ⅱ的转录起始复合物[7]。

TATA结合蛋白
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名TBP；, GTF2D, GTF2D1, HDL4, SCA17, TFIID, TATA-box binding protein, TATA-binding protein, TBP1
外部IDOMIM：600075 MGI：101838 HomoloGene：2404 GeneCards：TBP
相關疾病
spinocerebellar ataxia type 17[1]
基因位置（人类）
6號染色體
染色体6號染色體[2]
6號染色體
TATA结合蛋白的基因位置
TATA结合蛋白的基因位置
基因座6q27起始170,554,302 bp[2]
终止170,572,870 bp[2]
RNA表达模式
查阅更多表达数据
直系同源
物種人類小鼠
Entrez

6908

21374

Ensembl

ENSG00000112592

ENSMUSG00000014767

UniProt

P20226

P29037

mRNA​序列

NM_003194
​NM_001172085

NM_013684

蛋白序列

NP_001165556
​NP_003185

NP_038712

基因位置​（UCSC）Chr 6: 170.55 – 170.57 MbChr 17: 15.72 – 15.75 Mb
PubMed​查找[4][5]
維基數據
TBP
crystal structure of a yeast brf1-tbp-dna ternary complex
鑑定
標誌TBP
PfamPF00352（旧版）
Pfam宗系CL0407（旧版）
InterProIPR000814
PROSITEPDOC00303
SCOP1tbp / SUPFAM

蛋白质的相互作用

TATA结合蛋白与下列蛋白質进行互作：

参考文献
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