Singles
2021 Wiesbaden Tennis Open
Champion	Anna Bondár
Runner-up	Clara Burel
Score	6–2, 6–4

Barbora Krejčíková was the defending champion^[1] but chose not to participate.

Anna Bondár won the title, defeating Clara Burel in the final, 6–2, 6–4.

Seeds

Draw

Finals

	Semifinals							Final
	1	Clara Burel	4	6	6
	Q	Lina Gjorcheska	6	4	4
								1	Clara Burel	2	4
								3	Anna Bondár	6	6
	3	Anna Bondár	6	6
		Conny Perrin	2	3

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	C Burel	77	6
	Q	K Bartone	63	2				1	C Burel	6	64	6
	Q	L Papadakis	6	6				Q	L Papadakis	2	77	0
	WC	LI Putz	2	0											1	C Burel	77	6
		A Ignatik	6	6												A Ignatik	62	4
		T Mrdeža	3	1					A Ignatik	6	6
		M Di Giuseppe	77	77					M Di Giuseppe	2	3
	5	RL Jani	63	64																		1	C Burel	4	6	6
	4	M Melnikova	7	6																		Q	L Gjorcheska	6	4	4
		A Zaja	5	1				4	M Melnikova	3	5
		B Turati	63	7	65			Q	L Gjorcheska	6	7
	Q	L Gjorcheska	77	5	77										Q	L Gjorcheska	6	2
	LL	Y Morderger	77	1	3										8	F Di Sarra	1	0r
	WC	A Klasen	64	6	6			WC	A Klasen	4	5
		T Lukas	3	2				8	F Di Sarra	6	7
	8	F Di Sarra	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	7	L Stefanini	2	6	6
	Q	N Berberović	6	4	1			7	L Stefanini	6	64	6
	WC	K Kanev	3	0				Q	S Wagner	1	77	1
	Q	S Wagner	6	6											7	L Stefanini	3	3
		S Bandecchi	65	6	4										3	A Bondár	6	6
	JE	V Jiménez Kasintseva	77	4	6			JE	V Jiménez Kasintseva	2	2r
	Q	C Ferrando	0r					3	A Bondár	6	3
	3	A Bondár	5																			3	A Bondár	6	6
	6	G Gatto-Monticone	2	6	6																		C Perrin	2	3
	Q	A Hartono	6	1	2			6	G Gatto-Monticone	0	0
		C Perrin	6	6					C Perrin	6	6
	Q	A Roșca	4	1												C Perrin	6	6
	WC	M Hodzic	1	2												Y In-Albon	1	3
		K Gerlach	6	6					K Gerlach	2	4
		Y In-Albon	6	7					Y In-Albon	6	6
	2	C Bucșa	4	5

References

• Main Draw