ISIS is raided and disbanded by the U.S. government when it transpires that the agency was never sanctioned by them. Cyril, Pam, Cheryl, Krieger and Ray promptly spill the beans about all of ISIS's operations, while Lana and Archer creatively break out of custody, only to find that Malory has managed to get everyone off the hook, on the condition that ISIS be dismantled immediately. As the staff discuss what they all plan to do next, Archer reveals a hidden vault containing a ton of cocaine and Lana sarcastically suggests that they form a cartel. The episode ends with a montage of scenes from the rest of the season.^[1]

Disguised as a doctor and nurse, Archer and Lana take twenty kilos of cocaine - hidden in plaster covering Pam's entire body - to a deal with an unknown buyer. A nervous and sweaty Pam absorbs cocaine through her skin and ends up addicted - to the point of eating the plaster/cocaine body cast. They then meet with the buyer, who turns out to be Ramon. Ramon is making the buy on behalf of Rudy and Charles, all three last seen in the Season 1 episode "Honeypot." As the deal turns increasingly sour and all three buyers wind up dead, it is revealed in the final scene that it was an elaborate ruse to steal the cocaine from ISIS, pretend to be dead to throw suspicion, and to have paid ISIS in counterfeit bills. Meanwhile, Cheryl is beginning her goal of becoming a country music star, performing the original song "40 Miles of Mountain Road" in the background of the episode. Singer Jessy Lynn Martens provides her vocals. While horrible in rehearsals, it's discovered that when no one is watching her, Cheryl is an amazing singer, pushing Malory to become her agent.

The gang decides to use the counterfeit money to buy guns, but Pam takes it instead to buy amphetamines from the Yakuza. They trace Pam down (as she had left a full and detailed listing of living at Cheryl's mansion at her old apartment) as the Yakuza boss, Mr. Moto, demands the drugs be returned. He also wants Pam's head, and despite Cheryl offering to pay him, he still refuses. Cheryl reveals she has an entire arsenal of old-fashioned weapons the team uses to defend the mansion from Yakuza attackers. They manage to use the tunnels built under the mansion by one of Cheryl's crazy uncles to escape, and Archer cuts a deal with Moto to give away 5 million dollars worth of cocaine to even things up. Ron is shot and wounded in the attack and, as he's taken to the hospital, he refuses to support Malory's criminal lifestyle.

As the gang discusses their diminishing coke supply and sending Pam to rehab, an FBI agent knocks on the door. Because he was invited in by Woodhouse, the gang fears their coke pile will incriminate them under the plain view doctrine. Everyone scrambles to distract the FBI agent. The agent is fooled into leaving, and a computer chip is installed into Cheryl to remove her anxiety and allow her to become a country singer.

With Krieger operating an online pharmacy to distribute the cocaine to buyers, the gang has the free time to throw a neglected Lana a baby shower. Archer takes Pam along for backup on a trip to the Tuntmore Hotel to secure a very special shower gift: a performance by Kenny Loggins.

Without Malory's knowledge or permission, Archer takes some of the cocaine to South America, dragging Cyril and Ray along. Archer plans to simply ask around to find a drug lord named La Madrina and give her the cocaine as a sample for more. He ends up in bed with La Madrina only to discover that she's an undercover police officer who sends the trio to jail without backup.

Archer avoids crash landing in a dangerous swamp only to come face-to-face with a shady arms dealer. They manage to escape back to New York with a slate of illegal arms meant to be sent to a Central American country in civil war and Malory decides to sell the arms for money after discovering Krieger wasted the last of the cocaine on a failed submarine experiment.

Archer and the rest of the ISIS gang are the guests of Gustavo Calderon, dictator of fictional Central American country San Marcos, and his wife Juliana. Calderon is a big fan of Cherlene, but Juliana is a bigger fan of Archer, seducing him while disguised as a maid.

Archer tries to keep his fling with the dictator's wife a secret while Krieger bonds with his clone-brothers. Cyril, at the request of Malory to find an escape vehicle, steals a tank from Calderon's stockpile and uses it to force Calderon and his troops to surrender to him.

Cyril becomes the new president of San Marcos and forcibly takes Juliana as his wife, Cherlene becomes the first lady of country music, and Archer becomes a resistance fighter. Calderon is killed by a tiger after Cherlene lets it loose from Calderon's zoo. Lana's water breaks.

Archer and later Malory and Pam help Lana with the delivery of her baby while Krieger, who after fighting and defeating his clones does not sufficiently prove to Ray that he isn't one of the clones, and Ray try to prevent the launch of a deadly nerve gas rocket. Cyril is dethroned as 'leader' of San Marcos while Malory forces him and Pam to steal as many valuables from Calderon's mansion as possible. Krieger decides to take the nerve gas canister out of the rocket before it launches and reveals that Cherlene's brain chip was a placebo. Malory negotiates an underhanded deal with the CIA to reactivate ISIS (involving the CIA taking the nerve gas). Lana reveals to Archer that he is the father of her baby girl since she took a sample of his sperm due to his physical specimen and her attraction to him.