E. W. Kemble's "Death's Laboratory" on the cover of Collier's (June 3, 1905)
A patent medicine, also known as a proprietary medicine or a nostrum (from the Latin nostrum remedium, or "our remedy") is a commercial product advertised to consumers as an over-the-counter medicine, generally for a variety of ailments, without regard to its actual effectiveness or the potential for harmful side effects. The earliest patent medicines were created in the 17th century. They were most popular from the mid-19th century to the early 20th century, before the advent of consumer protection laws and evidence-based medicine.[1][2] Despite the name, patent medicines were usually trademarked but not actually patented, in order to keep their formulas secret.[3][4]
Patent medicines often included alcohol and drugs such as opium as active ingredients.[5] Addiction and overdose were common as a result.[6][7] Some formulations included toxic ingredients such as arsenic, lead, and mercury.[8] Other ingredients like sarsaparilla and wintergreen may have been medically inert and largely harmless, but lacked significant medical benefits.[9] It was rare for any patent medication to be pharmacologically effective, and none lived up to the miraculous promises made by their advertising.[9]
Patent medicine advertising was typically outlandish, eye-catching, and had little basis in reality.[10] Advertisements emphasized exotic or scientific-sounding ingredients, featured endorsements from purported experts or celebrities, and often claimed that products were universal remedies or panaceas.[11] Beginning in the early 20th century, the passage of consumer protection laws in countries like the United Kingdom, United States, and Canada began to regulate deceptive advertising and put limits on what ingredients could be used in medicines, putting an end to the dominance of patent medicines.[2][12][13] Although some modern alternative medicines bear similarities to patent medicines, the term most typically refers to remedies created before modern regulations, and the scope of this list reflects that.[14][15][16][17]
Types of patent medicine
1889 lithograph advertisement
Various types of pre-scientific medical preparations, some based on folk or traditional remedies, were sold as patent medicines.[18] Because patent medicines were unscientific and unregulated, the brand names of many products were not necessarily an accurate reflection of their ingredients or preparation methods.
- Aphrodisiac: patent medicine advertisements often claimed aphrodisiac effects, the language of which ranged from euphemistic hints at "re-animation" and "potency" to extremely blatant promises of "sexual rejuvenescence."[19][20][21]
- Balsam: a solution of plant-specific resins in plant-specific solvents (essential oils); balsams have been used in medicine since prehistory.[22][23][18]
- Coca wine: an infusion of coca leaves in red wine invented by chemist Angelo Mariani in the 1860s, which later spawned numerous imitators.[24][25][26]
- Cordial: a sweetened alcohol-based concoction intended to be stimulating to the heart, often containing numerous herbs; some cordials are now sold non-medically as liqueurs.[18][27]
- Elixir: similar to a cordial, an elixir was historically defined as a sweet liquid containing one or more active ingredients, taken as a medical remedy.[18][28]
- Fruit salt: an effervescent compound made up of organic acids, salts, added flavoring, and sugar.[29]
- Herbal tonic: a loosely-defined category of traditional herbal medicines with various ingredients and intended purposes.[30]
- Liniment: a topical medication, sometimes called a balm or heat rub, intended for application to the skin for the relief of pain and stiffness.[31]
- Lithia water: mineral water characterized by the trace presence of lithium salts; popular in the United States between the 1880s and World War I.[32]
- Panacea: patent medicines were often sold as panaceas, or universal cures.[33]
- Snake oil: the archetypal quack remedy, cure-all medicines purportedly made of snake oil were so popular in the 19th century that the phrase is now used as a generic term for hoaxes of all kinds.[34]
- Tincture: an extract of organic material dissolved in alcohol, tinctures are still used in modern herbal medicine.[35][36]
- Vermifuge: before modern sanitation practices, intestinal parasite infections were common; a variety of worm lozenges, powders, and syrups, commonly including santonin, were sold as treatment.[37][38][39]
Notable brand names
Surviving brands and products
Early 20th-century advertisement
A bottle of Fernet-Branca herbal liqueur
Some brands from the patent medicine era have survived into the present day, typically with significantly revised formulas and toned-down advertising. Some are still sold as medicines, with more realistic claims and less harmful ingredients. Many others, particularly liquid preparations, have been revised into non-medical food or drink products such as soft drinks.[14]
- 7 Up: this soft drink was originally named "Bib-Label Lithiated Lemon-Lime Soda"; it contained lithium citrate, a mood-stabilizing drug, until 1948.[40]
- Angostura bitters: originally marketed as a remedy for seasickness, angostura bitters are now used as a common cocktail ingredient.[41]
- Black Draught: a mixture of saline aperient and blue mass prescribed as a purgative, historically popular with African Americans.[42][43]
- Buckfast Tonic Wine: a caffeinated fortified wine originally marketed as a health tonic, now marketed simply as an alcoholic drink.[44][45]
- Carter's Little Liver Pills: originally touted as a cure for headache, constipation, dyspepsia, and biliousness, now marketed as a basic laxative.[46]
- Coca-Cola: originally marketed as a cure for ailments including morphine addiction and impotence; eventually reformulated as a soft drink without medicinal ingredients.[47]
- Dr Pepper: early advertisements for this soft drink made medical claims, stating that it "aids digestion and restores vim, vigor, and vitality."[48][49]
- Eno: a brand of fruit salt originally promoted as a cure-all; successfully rebranded in the 1950s as an antacid drug.[29][50]
- Father John's Medicine: originally consisting of cod-liver oil and licorice root, this cough medicine was later reformulated to include dextromethorphan, and is still sold today.[51]
- Fernet-Branca: this brand of amaro liqueur was originally promoted as a cure for overeating and hangovers, and remains a popular digestif.[52]
- Fletcher's Laxative: originally sold as Pitcher's Castoria and later Fletcher's Castoria, it was reformulated to remove alcohol and is still sold as a children's laxative.[5]
- Hires Root Beer: originally marketed with claims that it could "purify the blood and make rosy cheeks," it is now sold as a non-medicinal soft drink.[49]
- Lithia: a brand of lithia water once advertised as a treatment for depression, alcoholism, and low libido, now sold without health claims.[53]
- Mentholatum Ointment: introduced in 1894, early advertising focused on the perceived exoticism of menthol by calling it the "Great Japanese Salve Mentholatum".[54]
- Minard's Liniment: although meant for external use, Minard's was sometimes taken internally in Newfoundland and Labrador as a home remedy for the common cold.[55][56]
- Moxie: created around 1876 as a patent medicine called "Moxie Nerve Food," this is now a popular New England soft drink.[49][57]
- Pepsi: this popular soft drink was first sold as a digestive aid, and takes its name from the Greek word for digestion.[58]
- Sanatogen: sold in the 1920s as a remedy for depression, the brand name persists as a fortified wine, with a label warning that it "does not imply health-giving or medicinal properties."[59]
- Smith Brothers Cough Drops: one of the first trademarked products in the United States, the brand disappeared in the 1970s, but was revived in 2016.[60][61]
- Zam-Buk: introduced in 1902 with typically exaggerated claims, this ointment is still produced, and is considered a cultural staple in South Africa.[62][63]
Discontinued products
Antique bottles of Daffy's Elixir, Dalby's Carminative and Turlington's Balsam of Life
Dr. Williams' Pink Pills for Pale People
Advertising poster from about 1890
.jpg.webp)
A bottle of Radithor at the National Museum of Nuclear Science & History
1894 advertisement poster for Vin Mariani, lithograph by Jules Chéret
- A.B.C. Liniment: named for its three primary ingredients, aconite, belladonna, and chloroform, the toxic formula caused numerous poisonings and at least one death.[64][65][66]
- Água de Inglaterra: a name used for preparations using the bark of the cinchona tree, used to treat malaria in Portugal from the 17th to the 19th centuries.[67]
- Antikamnia: supposed pain medication containing acetanilid, which caused several deaths, after which it was reformulated to use the less toxic derivative acetphentidin.[68][69]
- Beecham's Pills: purportedly made of medicinal herbs; analysis by the British Medical Association in 1909 found they were made solely of aloe, ginger, and soap.[70]
- Bile Beans: a laxative and tonic first marketed in the 1890s, supposedly able to "disperse unwanted fat" and "purify and enrich the blood".[71][72]
- Buffalo Lithia Water: a brand of lithia water found to contain so little lithium that obtaining a therapeutic dose would require consuming at least 150,000 gallons daily.[73]
- Chlorodyne: this combination of laudanum, tincture of cannabis, and chloroform was marketed as a cure-all, but frequently caused addiction and overdoses.[7]
- Daffy's Elixir: a name used for multiple formulas sold as stomach remedies and cure-alls during the 18th and 19th centuries.[74]
- Dalby's Carminative: this opium-based medicine was marketed for calming babies, but was condemned by physicians of the time as potentially fatal to infants.[75]
- Dr. Bateman's Pectoral Drops: an opium solution sold during the 18th to 20th centuries as a remedy for chest and lung ailments.[76]
- Dr. Morse's Indian Root Pills: production of these cure-all pills formed the backbone of the economy for Morristown, New York for much of the 20th century.[77]
- Dr. Rush's Bilious Pills: laxatives containing more than 50% mercury, created by Benjamin Rush and famously taken on the Lewis and Clark Expedition of 1803–1806.[78][79]
- Dr. Thomas' Eclectric Oil: the name of this cure-all is a portmanteau of "eclectic" and "electric", referencing the then-current theory that electricity had healing properties.[80]
- Dr. Williams' Pink Pills for Pale People: these bright pink pills, largely composed of iron, were actually an effective treatment for anemia and chlorosis.[81]
- Fowler's solution: an arsenical compound sold in the 19th century for various ailments including treatment of leukemia.[82][83]
- Godbold's Vegetable Balsam: a mixture of sublimate of mercury, gum Arabic, honey, and syrup sold in the 18th and 19th centuries as a cure for syphilis.[84]
- Godfrey's Cordial: called "Mother's Friend," this laudanum cordial was used to quiet infants, but frequently caused serious or even lethal opium poisoning.[85]
- Green's August Flower: a tonic for indigestion often sold with the company's other major product, Dr. Boschee's Syrup, a purported cure for tuberculosis.[86]
- Hadacol: marketed as a vitamin supplement in the United States during the 1940s and 1950s, it was primarily popular in dry counties for its alcohol content.[87][88]
- Hamlin's Wizard Oil: a cure-all produced by former magician John Hamlin, popularly sold at gaudy medicine shows throughout the American Midwest in the 19th century.[89][90]
- Jamaica ginger: popular during the era of alcohol prohibition in the United States as it was available as a medication, but contained approximately 70% to 80% ethanol by weight.[91][92]
- Keyser's Pills: an 18th-century patent medicine containing mercuric oxide and acetic acid, used to treat syphilis.[93][94]
- Lane's Emulsion: invented in New Zealand and promoted as a health tonic and a cure for tuberculosis.[95]
- Londonderry Lithia: advertised as a cure-all, this brand of lithia water went out of business after government tests found it contained no more than trace amounts of lithium.[96]
- Mrs. Moffat's Shoo-Fly Powders for Drunkenness: a supposed remedy for intoxication which in 1941 was the subject of one of the first court cases brought by the Food and Drug Administration of the United States.[97][98]
- Mrs. Winslow's Soothing Syrup: a morphine syrup that remained on the market until 1930, despite claims as early as 1911 that it was potentially lethal to infants.[99][100]
- Nine oils: a 19th-century preparation used on both horses and humans; druggists' books sometimes specified recipes, but quack cure salesmen often promoted any kind of oil as the "nine oils".[101][102]
- Orvietan: this herbal concoction was used in the 17th and 18th centuries as a panacea against various types of poisoning and other maladies.[103][104]
- Oxygenized air: a form of laughing gas promoted as a cure for various diseases of the respiratory tract.[105][106]
- Pemberton's French Wine Coca: a coca wine invented by druggist John Stith Pemberton, the inventor of Coca-Cola.[107]
- Peruna: sold as a cure for catarrh, this patent medicine was so popular that it became the namesake of the mascot of Southern Methodist University.[108]
- Phospho-Energon: a Swedish preparation from the early 20th century whose main ingredients were calf's brain, sugar and milk.[109][110]
- Radithor: American socialite Eben Byers died of radiation-induced cancer in 1932 after consuming this radioactive quack medicine.[111]
- Sedna: an Irish port wine marketed as a health tonic, its original formula contained coca leaves, kola nuts, and beef extract.[112]
- Sequah Medicine Company: this company toured England with a promotional medicine show featuring exaggerated depictions of cowboys and Native Americans.[113]
- Seven Sutherland Sisters Hair Grower: a hair growth formula promoted by the Sutherland Sisters, famed for their own floor-length hair.[114]
- Soliman's Water: a 16th-century facial peel made of mercury, sulfur, and turpentine; while effective in the short term, it could cause long-term damage like mercury poisoning.[115]
- Soloman's Cordial Balm of Gilead: a famous and expensive remedy exposed as a fraud when its ingredients were discovered to be nothing more than French brandy infused with lemon peel and cardamom seeds.[116][117]
- Swaim's Panacea: first sold by William Swaim in 1820, this popular remedy was composed of sarsaparilla syrup, oil of wintergreen, and corrosive sublimate of mercury.[118][119]
- Tilden's Extract: a medicinal cannabis extract popularized by American author Fitz Hugh Ludlow in his 1857 book The Hasheesh Eater.[120][121]
- Turlington's Balsam: English merchant Robert Turlington was granted a royal patent for this 27-ingredient preparation in 1744, making it one of the earliest patented medicines.[122][123][124]
- Vin Mariani: the original coca wine, Vin Mariani was sold as a medicine and performance enhancer and endorsed by numerous celebrities, including Pope Leo XIII and Thomas Edison.[125][126]
- Warburg's tincture: an efficacious but now-obsolete remedy for malaria, it was sometimes criticized as a quack remedy until the formula was released in 1875.[127][128][129]
See also
References
- ↑ "Balm of America: Patent Medicine Collection -- History". National Museum of American History. Archived from the original on 2019-11-01. Retrieved 2019-09-13.
- 1 2 "Patent Medicine, 1860-1920". Digital Public Library of America. Archived from the original on 2019-10-13. Retrieved 2019-09-13.
- ↑ "History of Patent Medicine". Hagley. 2017-04-10. Archived from the original on 2019-08-22. Retrieved 2019-08-22.
- ↑ Janik, Erika (2014-01-07). Marketplace of the Marvelous: The Strange Origins of Modern Medicine. Beacon Press. ISBN 9780807022092.
- 1 2 Kyle, Robert A.; Steensma, David P. (2017-09-01). "Charles Fletcher, The Centaur Company, and Proprietary Medicine Revenue Stamps". Mayo Clinic Proceedings. 92 (9): e127–e128. doi:10.1016/j.mayocp.2017.06.021. ISSN 0025-6196. PMID 28870369.
- ↑ Agnew, Jeremy (2010-04-23). Medicine in the Old West: A History, 1850-1900. McFarland. ISBN 9780786456031.
- 1 2 Parker, R. R.; Cobb, J. P.; Connell, P. H. (March 1974). "Chlorodyne dependence". Br Med J. 1 (5905): 427–9. doi:10.1136/bmj.1.5905.427. PMC 1633222. PMID 4816855.
- ↑ "First tests of old patent medicine remedies from a museum collection". American Chemical Society. Archived from the original on 2019-12-19. Retrieved 2019-12-18.
- 1 2 Parascandola, John (1999). "Patent Medicines and the Public's Health". Public Health Reports. 114 (4): 320–321. doi:10.1093/phr/114.4.318. ISSN 0033-3549. JSTOR 4598417. PMC 1308491. PMID 10501130.
- ↑ Janik 2014, p. 118.
- ↑ Loeb, Lori (2001). "Doctors and Patent Medicines in Modern Britain: Professionalism and Consumerism". Albion: A Quarterly Journal Concerned with British Studies. 33 (3): 409–410. doi:10.2307/4053198. ISSN 0095-1390. JSTOR 4053198. PMID 18300407.
- ↑ Gale, Nicola K.; McHale, Jean V. (2015-04-10). Routledge Handbook of Complementary and Alternative Medicine: Perspectives from Social Science and Law. Routledge. ISBN 9781136685552.
- ↑ Boisrobert, Christine E.; Stjepanovic, Aleksandra; Oh, Sangsuk; Lelieveld, Huub L.M., eds. (2010). "Chapter 2 - Development of Food Legislation Around the World". Ensuring Global Food Safety. Academic Press. doi:10.1016/C2009-0-01854-6. ISBN 978-0-12-374845-4.
- 1 2 Sfetcu, Nicolae (2014-05-02). Health & Drugs: Disease, Prescription & Medication.
- ↑ Aronson, Jeffrey K (2009). "Patent medicines and secret remedies". BMJ: British Medical Journal. 339 (7735): 1396. doi:10.1136/bmj.b5415. ISSN 0959-8138. JSTOR 25673512. PMID 20008435. S2CID 22420837.
- ↑ Uretsky, Samuel; Birdsall, Carole (1986). "Quackery: A Thoroughly Modern Problem". The American Journal of Nursing. 86 (9): 1031–1032. doi:10.2307/3425579. ISSN 0002-936X. JSTOR 3425579. PMID 3638913.
- ↑ "Definition of PATENT MEDICINE". www.merriam-webster.com. Archived from the original on 2017-08-18. Retrieved 2019-12-18.
- 1 2 3 4 Kelly, James (2008). "Health for sale: mountebanks, doctors, printers and the supply of medication in eighteenth-century Ireland". Proceedings of the Royal Irish Academy. Section C: Archaeology, Celtic Studies, History, Linguistics, Literature. 108C: 78. doi:10.1353/ria.2008.0006. ISSN 0035-8991. JSTOR 40657923. S2CID 245846177.
- ↑ Young, James Harvey (1993). "Sex Fraud". Pharmacy in History. 35 (2): 65–69. ISSN 0031-7047. JSTOR 41111519. PMID 11623341.
- ↑ Twitchell, James B. (2000). 20 Ads that Shook the World: The Century's Most Groundbreaking Advertising and how it Changed Us All. Three Rivers Press. pp. 30–31. ISBN 9780609807231.
- ↑ Silverstein, Ken (2005). The Radioactive Boy Scout: The Frightening True Story Of A Whiz Kid And His Homemade Nuclear Reactor. Villard. ISBN 9780812966602.
- ↑ Klemens Fiebach; Dieter Grimm (2007), "Resins, Natural", Ullmann's Encyclopedia of Industrial Chemistry (7th ed.), Wiley, p. 2, doi:10.1002/14356007.a23_073
- ↑ Milwright, Marcus (2003). "The Balsam of Maṭariyya: An Exploration of a Medieval Panacea". Bulletin of the School of Oriental and African Studies, University of London. 66 (2): 193–209. doi:10.1017/S0041977X03000119. ISSN 0041-977X. JSTOR 4145845. S2CID 163105374.
- ↑ Feiling, Thomas (2012-02-15). Cocaine Nation: How the White Trade Took Over the World. Pegasus Books. ISBN 9781681770048.
- ↑ Platt, Jerome J. (2000-05-05). Cocaine Addiction: Theory, Research, and Treatment. Harvard University Press. ISBN 9780674001787.
- ↑ Lestrange, Aymon de (2018-12-18). Coca Wine: Angelo Mariani's Miraculous Elixir and the Birth of Modern Advertising. Simon and Schuster. ISBN 9781620557853.
- ↑ Times, CHARLES PERRY Los Angeles. "TAKING YOUR MEDICINE WAS A CORDIAL AFFAIR". Sun-Sentinel.com. Archived from the original on 2019-09-24. Retrieved 2019-09-23.
- ↑ Chisholm, Hugh, ed. (1911). . Encyclopædia Britannica. Vol. 9 (11th ed.). Cambridge University Press. pp. 281–282.
- 1 2 Crellin, John K. (2004). A social history of medicines in the twentieth century: to be taken three times a day. New York: Pharmaceutical Products Press. p. 154. ISBN 9780789018458.
- ↑ Watson, Ronald Ross; Preedy, Victor R. (2008). Botanical Medicine in Clinical Practice. CABI. p. 823. ISBN 9781845934132.
- ↑ Calvert, Robert Noah (April 2002). The History of Massage: An Illustrated Survey from Around the World. Inner Traditions / Bear & Co. ISBN 9780892818815.
- ↑ Bullard, Loring (2004). Healing Waters: Missouri's Historic Mineral Springs and Spas. University of Missouri Press. p. 96. ISBN 9780826264183.
- ↑ Young, James Harvey (1961). "Chapter 11: The Pattern of Patent Medicine Appeals". The Toadstool Millionaires. Princeton University Press. ISBN 9780691646855. Archived from the original on 2017-02-23. Retrieved 2019-12-16.
- ↑ Graber, Cynthia. "Snake Oil Salesmen Were on to Something". Scientific American. Archived from the original on 2007-11-18. Retrieved 2019-09-24.
- ↑ Romm, Aviva (2017-01-25). Botanical Medicine for Women's Health E-Book. Elsevier Health Sciences. p. 53. ISBN 9780702065132.
- ↑ Mackintosh, Alan (2017-12-04). The Patent Medicines Industry in Georgian England: Constructing the Market by the Potency of Print. Springer. p. 96. ISBN 9783319697789.
- ↑ History, Bill Kemp | Archivist/librarian McLean County Museum of. "Intestinal worms were once a common menace to all classes". pantagraph.com. Archived from the original on 2019-12-16. Retrieved 2019-12-16.
- ↑ Nostrums & Patent Medicines. North Dakota Agricultural College. 1916. p. 239.
- ↑ Hiss, A. Emil (1898). Thesaurus of Proprietary Preparations and Pharmaceutical Specialties: Including "patent" Medicines, Proprietary Pharmaceuticals, Open-formula Specialties, Synthetic Remedies, Etc. G. P. Engelhard. p. 266.
- ↑ Tiekink, Edward R.T.; Gielen, Marcel (2005). Metallotherapeutic Drugs and Metal-based Diagnostic Agents : The Use of Metals in Medicine. Chichester: John Wiley and Sons. p. 3. ISBN 978-0470864036.
- ↑ Barnett, Richard (2012-04-14). "Bitter medicine: gout and the birth of the cocktail". The Lancet. 379 (9824): 1384–1385. doi:10.1016/S0140-6736(12)60586-8. ISSN 0140-6736. PMID 22509528. S2CID 791211.
- ↑ Watson, Wilbur (1998-01-01). Black Folk Medicine: The Therapeutic Significance of Faith and Trust. Transaction Publishers. p. 54. ISBN 9781412818773.
- ↑ Crowder, Steve, "Black Folk Medicine in Southern Appalachia Archived 2019-08-22 at the Wayback Machine." (2001). Electronic Theses and Dissertations. Paper 149, p. 24.
- ↑ "History of the Tonic Wine". Buckfast Abbey. Archived from the original on 29 December 2013. Retrieved 26 December 2013.
- ↑ "Buckfast tonic wine hits record £43.2m sales high". www.thedrinksbusiness.com. 10 January 2018. Archived from the original on 23 August 2019. Retrieved 23 August 2019.
- ↑ "Carter's Little Liver Pills". Lowcountry Digital Library. Archived from the original on 3 September 2014. Retrieved 1 September 2014.
- ↑ Pendergrast, Mark (2000). For God, Country, and Coca-Cola. New York: Basic Books. p. 32. ISBN 9780465046997.
- ↑ Bloom, John (April 1978). "Business: Sweet Revenge". Texas Monthly. Emmis Communications. p. 78. Archived from the original on 2021-01-26. Retrieved 2019-08-31.
- 1 2 3 Pendergrast 2000, p. 13.
- ↑ Crellin, John K. (2004). A social history of medicines in the twentieth century : to be taken three times a day (Reprint. ed.). New York: Pharmaceutical Products Press. p. 154. ISBN 9780789018458.
- ↑ Kreidler, Marc (2014-04-23). "Father John's Medicine | Center for Inquiry". Archived from the original on 2019-08-23. Retrieved 2019-08-23.
- ↑ Curtis, Wayne (2008-11-01). "The Bitter Beginning". The Atlantic. Archived from the original on 2019-08-23. Retrieved 2019-08-23.
- ↑ May, Lee (1989-12-04). "Business is bubbling again as lithium-water drinkers swear by its healing powers". Los Angeles Times. Archived from the original on 2019-09-03. Retrieved 2019-09-03.
- ↑ "History of the Mentholatum Company". Buffalo Rising. 2017-03-26. Archived from the original on 2019-12-19. Retrieved 2019-12-18.
- ↑ "Minard's King of Pain Liniment". National Museum of American History. Archived from the original on 2019-09-03. Retrieved 2019-09-03.
- ↑ Crellin, J. K. (1994). Home Medicine: The Newfoundland Experience. Vol. 1. McGill-Queen's Press - MQUP. p. 118. ISBN 9780773511972. PMID 11618571.
{{cite book}}:|journal=ignored (help) - ↑ Waugh, Danielle (2018-08-29). "Maine Split on Coca-Cola's Acquisition of Moxie". NBC10 Boston. Archived from the original on 2019-01-27. Retrieved 2019-01-26.
- ↑ Wu, Tim (September 2017). The Attention Merchants: The Epic Scramble to Get Inside Our Heads. New York: Vintage Book. p. 156. ISBN 978-0-385-35202-4. Retrieved 2019-09-02.
- ↑ Jarvis, Alice-Azania (2014-07-08). "Eight of the most outlandish food health claims". The Guardian. ISSN 0261-3077. Archived from the original on 2019-09-02. Retrieved 2019-09-02.
- ↑ D'Antonio, Michael (2007-01-09). Hershey: Milton S. Hershey's Extraordinary Life of Wealth, Empire, and Utopian Dreams. Simon and Schuster. p. 52. ISBN 9780743264105.
- ↑ Platt, Frances Marion (26 December 2017). "Poughkeepsie's own Smith Brothers Cough Drops make a comeback". Hudson Valley One. Archived from the original on 2019-09-02. Retrieved 2019-09-02.
- ↑ Crellin 1994, p. 72.
- ↑ Thomas, Jeremy. "Nampak index shows SA needs its Zam-Buk". Business Live. Archived from the original on 2019-12-16. Retrieved 2019-12-16.
- ↑ Everybody's Family Doctor. London, UK: Odhams Press LTD. 1935. p. 7.
- ↑ Weir, Archibald (February 15, 1896). "Fatal Case Of Poisoning By A.B.C. Liniment". The British Medical Journal. 1 (1833): 399–400. doi:10.1136/bmj.1.435.399-a. S2CID 19739440.
- ↑ Fisher, O D. (November 1954). "Accidental Poisoning of Children in Belfast: A Report of two years' experience at the Royal Belfast Hospital for Sick Children". Ulster Med J. 23 (2): 124–131. PMC 2480209. PMID 20476409.
- ↑ D'Esaguy, Augusto (May 1936). "Água de Inglaterra". Bulletin of the Institute of the History of Medicine. 4 (5): 404–408. JSTOR 44438162.
- ↑ Graves, W. H. (1905-07-22). "The Dangers of Acetanilid". JAMA: The Journal of the American Medical Association. XLV (4): 252. doi:10.1001/jama.1905.02510040024010. ISSN 0098-7484. S2CID 71963503.
- ↑ Rowell, Hubert N. (1907). "Poisoning by Antikamnia". California State Journal of Medicine. 5 (12): 326. ISSN 0093-402X. PMC 1652258. PMID 18734242.
- ↑ British Medical Association (1909). Secret remedies: what they cost and what they contain. Harold B. Lee Library. London: British Medical Association. pp. 175.
- ↑ Spiegl, Fritz (1996). Sick Notes: An Alphabetical Browsing-Book of Derivatives, Abbreviations, Mnemonics and Slang for Amusement and Edification of Medics, Nurses, Patients and Hypochondriacs. CRC Press. p. 22. ISBN 978-1-85070-627-4.
- ↑ Hensley, Scott (20 January 2011). "Annals Of Weight-Loss Gimmicks: From Bile Beans To Obesity Soap". Shots: Health News from NPR. NPR. Archived from the original on 30 January 2015. Retrieved 15 February 2015.
- ↑ Johnson, Frederick Neil (1984-06-18). The History of Lithium Therapy. Springer. p. 21. ISBN 9781349072897.
- ↑ "Daffys elixir - Dawsons lozenges". British History Online. Archived from the original on 2019-08-23. Retrieved 2019-08-23.
- ↑ The Western Journal of Medicine and Surgery. Prentice & Weissinger. 1844. p. 157.
- ↑ Richard Reece, 'Bateman's Pectral Drops,' The Monthly Gazette of Health; or Medical Dietetic, Antiempirical, and General Philosophical Journal, Vol. VI, 807.
- ↑ Shaw, Robert B. (1972). "History of the Comstock Patent Medicine Business and Dr. Morse's Indian Root Pills". Smithsonian Studies in History and Technology (22): 1–48. doi:10.5479/si.00810258.22.1. hdl:10088/2421. PMID 11633173.
- ↑ Woodger, Elin; Toropov, Brandon (2009). Encyclopedia of the Lewis and Clark Expedition. Infobase Publishing. pp. 304–06. ISBN 9781438110233.
- ↑ Duncan, Dayton; Burns, Ken (1997). Lewis & Clark: The Journey of the Corps of Discovery. New York: Alfred A. Knopf, Inc. pp. 9–10. ISBN 9780679454502.
- ↑ Sullivan, Catherine (May 1984). "Dr. Thomas' Eclectric Oil" (PDF). Parks Canada History. Archived (PDF) from the original on 2020-11-27. Retrieved 2020-02-15.
- ↑ Loeb, Lori (1999). "George Fulford and Victorian Patent Medicine Men: Quack Mercenaries or Smilesian Entrepreneurs?". Canadian Bulletin of Medical History. 16 (1): 125–45. doi:10.3138/cbmh.16.1.125. PMID 14531402.
- ↑ Jolliffe, D. M. (1993). "A history of the use of arsenicals in man". Journal of the Royal Society of Medicine. 86 (5): 287–289. doi:10.1177/014107689308600515. PMC 1294007. PMID 8505753.
- ↑ Doyle, Derek (2009). "Notoriety to respectability: a short history of arsenic prior to its present day use in haematology". British Journal of Haematology. 145 (3): 309–317. doi:10.1111/j.1365-2141.2009.07623.x. PMID 19298591. S2CID 6676910.
- ↑ Lane, Joan (2001). A Social History of Medicine: Health, Healing and Disease in England, 1750-1950. Oxon: Routledge. p. 152. ISBN 9781135119270.
- ↑ C., T. E. (1 June 1970). "What were Godfrey's Cordial and Dalby's Carminative?". Pediatrics. 45 (6). ISSN 0031-4005. Archived from the original on 18 October 2018. Retrieved 23 August 2019.
- ↑ Higby, Gregory; Pharmacy, American Institute of the History of (2001). Apothecaries and the Drug Trade: Essays in Celebration of the Work of David L. Cowen. Amer. Inst. History of Pharmacy. ISBN 9780931292361.
- ↑ Anderson, Ann (2000). Snake Oil, Hustlers and Hambones: The American Medicine Show. Jefferson: McFarland & Company. p. 149. ISBN 9781476601120.
- ↑ Stinnett, Chuck (Feb 2, 2010). "Chuck Stinnett column: Hadacol, with its splash of alcohol, was a sensation for a while". Evansville Courier & Press. Archived from the original on 2019-08-23. Retrieved 2019-08-23.
- ↑ Anderson 2000, p. 112.
- ↑ McNamara, Brooks (October 1995). Step right up (Revised ed.). University Press of Mississippi. p. 67. ISBN 9780878058310.
- ↑ Parascandola, John (May–June 1995). "The Public Health Service and Jamaica Ginger Paralysis in the 1930s". PHS Chronicles. 110 (3): 361–363. PMC 1382135. PMID 7610232.
- ↑ Gussow, Leon (October 2004). "The Jake Walk and Limber Trouble: A Toxicology Epidemic". Emergency Medicine News. 26 (10): 48. doi:10.1097/00132981-200410000-00045. ISSN 1054-0725.
- ↑ Louis-Courvoisier M (2007)An 18th century controlled trial prompted by a potential shortage of hospital beds. Archived 2019-09-01 at the Wayback Machine, JLL Bulletin: Commentaries on the history of treatment evaluation
- ↑ Conner, Susan P. The Pox in Eighteenth-Century France, in The Secret Malady: Venereal Disease in Eighteenth-century Britain and France, p. 25
- ↑ "Victorian Heritage Celebrations and the story of Lane's Emulsion | Culture Waitaki". culturewaitaki.org.nz. Archived from the original on 2019-09-01. Retrieved 2019-09-01.
- ↑ Holmes, Richard. "Londonderry's brief bottled water fame". The Derry News. Archived from the original on 2019-09-03. Retrieved 2019-09-03.
- ↑ Smith, Mickey C. (1988-12-31). Principles of Pharmaceutical Marketing, Third Edition. Psychology Press. pp. 487–. ISBN 9780866569354. Archived from the original on 2017-03-19. Retrieved 1 January 2013.
- ↑ McClellan, Mark B (August 8, 2003). "Speech before National Press Club". FDA. Archived from the original on 10 February 2012. Retrieved 10 January 2013.
- ↑ "Nostrums and Quackery; Articles on the Nostrum Evil and Quackery". Internet Archive. Chicago, IL.: American Medical Association. 1911. p. 318.
- ↑ "Mrs. Winslow's Soothing Syrup". Wood Library Museum. Archived from the original on 9 September 2016. Retrieved 5 September 2016.
- ↑ Victorian London - Publications - Social Investigation/Journalism - Toilers in London, by One of the Crowd [James Greenwood], [1883] - Doctor Quackinbosh Archived 2019-11-28 at the Wayback Machine
- ↑ FRANCIS, George William (1853). The Dictionary of Practical Receipts; Containing the Arcana of Trade and Manufacture; Domestic Economy; Artistical, Ornamental&scientific Processes; Pharmaceutical and Chemical Preparations, Etc (3rd ed.). J. Allen, D. Francis.
- ↑ Gentilcore, David (1998). Healers and Healing in Early Modern Italy. Manchester University Press. p. 113. ISBN 9780719041990. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Gambaccini, Piero (2003-11-20). Mountebanks and Medicasters: A History of Italian Charlatans from the Middle Ages to the Present. McFarland. p. 144. ISBN 9780786416066. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Blood, C. L. (1875). "Persecution of New Ideas". Asher & Adams' New Columbian Rail Road Atlas and Pictorial Album of American Industry. Asher & Adams. Archived from the original on December 7, 2019. Retrieved October 21, 2015.
- ↑ Blood, C. L. (May 1, 1867). "Oxygenized Air". Lewiston Evening Journal. Archived from the original on October 24, 2021. Retrieved October 21, 2015.
- ↑ Hamblin, James (January 31, 2013). "Why we took cocaine out of soda". The Atlantic. Archived from the original on June 4, 2014. Retrieved August 30, 2013.
- ↑ Sullivan, Jack (May–June 2007). "The Peruna Story: Strumming That Old Catarrh" (PDF). Bottles and Extras. Federation of Historical Bottle Collectors: 28, 31. Archived (PDF) from the original on 2018-12-23. Retrieved 2019-09-02.
- ↑ Johannisson, Karin (2001-06-24). "Vad är egentligen ett läkemedel?". LäkemedelsVärlden (in Swedish). Archived from the original on 2010-08-21. Retrieved 2008-08-06.
- ↑ Hake, Carl-Magnus (2002-02-24). "Nyponextrakt, tuggummi och fusioner". LäkemedelsVärlden (in Swedish). Archived from the original on 2010-08-26. Retrieved 2008-08-06.
- ↑ "Death Stirs Action on Radium 'Cures'. Trade Commission Speeds Its Inquiry. Health Department Checks Drug Wholesalers. Autopsy Shows Symptoms. Maker of "Radithor" Denies It Killed Byers, as Does Victim's Physician in Pittsburgh. Walker Uses Apparatus. Friends Alarmed to Find Mayor Has Been Drinking Radium-Charged Water for Last Six Months". New York Times. April 2, 1932. Archived from the original on 2021-10-24. Retrieved 2011-10-01.
Federal and local agencies, as well as medical authorities in various parts of the country, were stirred to action yesterday as a result of the death of Eben M. Byers, wealthy Pittsburgh steel manufacturer and sportsman, who died here Wednesday at the Doctors' Hospital from causes attributed to radium poisoning resulting from the drinking of water containing radium in solution. ...
- ↑ Chríodáin, Louise Ní (15 Nov 2018). "Cocaine Tooth Powder – useful for toothache and spongy gums". The Irish Times. Archived from the original on 2018-11-15. Retrieved 2019-09-02.
- ↑ Wynbrandt, James (2015-01-27). The Excruciating History of Dentistry: Toothsome Tales & Oral Oddities from Babylon to Braces. St. Martin's Press. ISBN 9781466890145. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Hix, Lisa. "Untangling the Tale of the Seven Sutherland Sisters and Their 37 Feet of Hair". Collectors Weekly. Archived from the original on 2019-11-01. Retrieved 2019-09-18.
- ↑ Stewart, Susan (2017-12-15). Painted Faces: A Colourful History of Cosmetics. Amberley Publishing Limited. ISBN 9781445654003. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Wilson, Ben (2014-03-20). Decency and Disorder: The Age of Cant 1789-1837. Faber & Faber. ISBN 9780571317202. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Helfand, William H. (1989). "President's Address: Samuel Solomon and The Cordial Balm of Gilead". Pharmacy in History. 31 (4): 155. ISSN 0031-7047. JSTOR 41111251.
- ↑ Young, James Harvey (1961). "Chapter 5: Hercules and Hydra". The Toadstool Millionaires. Princeton University Press. ISBN 9780691646855. Archived from the original on 2017-02-23. Retrieved 2019-10-17.
- ↑ Griffenhagen, George B.; Bogard, Mary (1999). History of Drug Containers and Their Labels. Amer. Inst. History of Pharmacy. p. 78. ISBN 9780931292262. Archived from the original on 2021-10-24. Retrieved 2020-11-18.
- ↑ Ludlow, Fitz Hugh (1857). The Hasheesh Eater: Being Passages from the Life of a Pythagorean. Harper & brothers. pp. 64.
- ↑ Lee, Martin A. (2013-08-13). Smoke Signals: A Social History of Marijuana - Medical, Recreational and Scientific. Simon and Schuster. p. 32. ISBN 978-1-4391-0261-9.
- ↑ Kelly, Kate (2010). Old World and New: Early Medical Care, 1700–1840. Infobase Publishing. p. 98. ISBN 978-0-8160-7208-8.
- ↑ Kremers, Edward; Sonnedecker, Glenn (1986). Kremers and Urdang's History of Pharmacy. American Institute of the History of Pharmacy. p. 124. ISBN 978-0-931292-17-0.
- ↑ Griffenhagen, George B.; Bogard, Mary (1999). History of Drug Containers and Their Labels. Amer. Inst. History of Pharmacy. ISBN 9780931292262.
- ↑ Bock, Gregory R.; Whelan, Julie (2008-04-30). Cocaine: Scientific and Social Dimensions. John Wiley & Sons. pp. 7–8. ISBN 9780470514252.
- ↑ Inciardi, James A. (1992). The War on Drugs II. Mayfield Publishing Company. p. 6. ISBN 1-55934-016-9.
- ↑ Tamreihao, K.; Mukherjee, Saikat; Ningthoujam, Debananda S. (2019-11-18). Current Perspectives on Anti-Infective Agents. Bentham Science Publishers. pp. 229–230. ISBN 978-981-14-3272-9.
- ↑ The Medical Times and Gazette. J. & A. Churchill. 1857. p. 90.
- ↑ The Lancet, edition 1875-11-13, 'Professor Maclean, C.B., on the true composition and therapeutic value of Warburg's Tincture', pp. 716–718.
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