The Escherichia coli chromosome shows two main levels of global organization: macrodomains and replichores. Macrodomains were discovered by cytological studies. They contain loci showing the same intracellular positioning and choreography during the cell cycle.[1]

References

  1. ↑ Niki H, Yamaichi Y, Hiraga S (January 2000). "Dynamic organization of chromosomal DNA in Escherichia coli". Genes Dev. 14 (2): 212–23. doi:10.1101/gad.14.2.212. PMC 316355. PMID 10652275.
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