| MOSPD3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | MOSPD3, CDS3, NET30, Motile sperm domain containing 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 609125 MGI: 1916179 HomoloGene: 11406 GeneCards: MOSPD3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Motile sperm domain containing 3 is a protein that in humans is encoded by the MOSPD3 gene.[5]
Function
This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described.
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000106330 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037221 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: Motile sperm domain containing 3".
Further reading
- Glöckner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (October 1998). "Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes". Genome Research. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.
- Pall GS, Wallis J, Axton R, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM (December 2004). "A novel transmembrane MSP-containing protein that plays a role in right ventricle development". Genomics. 84 (6): 1051–9. doi:10.1016/j.ygeno.2004.08.017. PMID 15533722.
- Cabukusta B, Berlin I, van Elsland DM, Forkink I, Spits M, de Jong AW, Akkermans JJ, Wijdeven RH, Janssen GM, van Veelen PA, Neefjes J (December 2020). "Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs". Cell Reports. 33 (10): 108475. doi:10.1016/j.celrep.2020.108475. hdl:1887/3184381. PMID 33296653. S2CID 228090430.
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