Small nucleolar RNA SNORA64/SNORA10 family
Predicted secondary structure and sequence conservation of SNORA64
Identifiers
SymbolSNORA64
Alt. SymbolsU64
RfamRF00264
Other data
RNA typeGene; snRNA; snoRNA; HACA-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000594
PDB structuresPDBe

In molecular biology, small nucleolar RNA SNORA10 and small nuclear RNA SNORA64 are homologous members of the H/ACA class of small nucleolar RNA (snoRNA). This family of ncRNAs involved in the maturation of ribosomal RNA.[1] snoRNA in this family act as guides in the modification of uridines to pseudouridines.[2] This family includes the human snoRNAs U64 and ACA10 and mouse MBI-29.[3][4][5]

References

  1. ↑ Narayanan A, Lukowiak A, Jády BE, et al. (1999). "Nucleolar localization signals of box H/ACA small nucleolar RNAs". EMBO J. 18 (18): 5120–5130. doi:10.1093/emboj/18.18.5120. PMC 1171582. PMID 10487763.
  2. ↑ Kiss T (2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions". Cell. 109 (2): 145–148. doi:10.1016/S0092-8674(02)00718-3. PMID 12007400. S2CID 8968788.
  3. ↑ Ofengand J, Bakin A (1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". J. Mol. Biol. 266 (2): 246–268. doi:10.1006/jmbi.1996.0737. PMID 9047361.
  4. ↑ Kiss, Arnold M.; Jády, Beáta E.; Bertrand, Edouard; Kiss, Tamás (2004). "Human Box H/ACA Pseudouridylation Guide RNA Machinery". Molecular and Cellular Biology. 24 (13): 5797–5807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
  5. ↑ Schattner P, Barberan-Soler S, Lowe TM (2006). "A computational screen for mammalian pseudouridylation guide H/ACA RNAs". RNA. 12 (1): 15–25. doi:10.1261/rna.2210406. PMC 1370881. PMID 16373490.


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