JFCR39
JFCR39是日本癌研究會(Japanese Foundation for Cancer Research,JFCR)列出的39种人类癌症细胞系的列表[1],用于抗癌药物筛选等科学研究[2]。与美国国家癌症研究所列出的NCI-60相比,JFCR39删去了所有白血病细胞系,但增加了胃癌细胞系,肺癌中不止列出非小细胞肺癌,也包括小细胞肺癌,还增加了几个来自日本病人的细胞系[1]。JFCR后续又设立了只包括胃癌、肝癌与乳腺癌三类的JFCR45[3]。
细胞系
肺癌
细胞系 | 类型 | 性别 | 倍增时间 | 也列入 | 文献 | 外部链接 |
---|---|---|---|---|---|---|
NCI-H23 | 非小细胞肺癌 | 男 | 33.4h | NCI-60 | [4] | CVCL_1547 |
NCI-H226 | 非小细胞肺癌 | 男 | 61h | NCI-60 | [4] | CVCL_1544 |
NCI-H522 | 非小细胞肺癌 | 男 | 38.2h | NCI-60 | [4] | CVCL_1567 |
NCI-H460 | 非小细胞肺癌 | 男 | 17.8h | NCI-60 | [4] | CVCL_0459 |
A549 | 非小细胞肺癌 | 男 | 22.9h | NCI-60 | [5] | CVCL_0023 |
DMS 273 | 小细胞肺癌 | 女 | 6.2 d | [6] | CVCL_1176 | |
DMS 114 | 小细胞肺癌 | 男 | 27h | NCI-60附加列表 | [7] | CVCL_1174 |
胃癌
细胞系 | 性别 | 倍增时间 | 也列入 | 文献 | 外部链接 |
---|---|---|---|---|---|
St-4 | ? | ? | JFCR45 | [8] | CVCL_H265 |
MKN-1 | 男 | 43-45h | JFCR45 | [9] | CVCL_1415 |
MKN-7 | 男 | 64-66h | JFCR45 | [10] | CVCL_1417 |
MKN-28 | 男 | 28-32h | JFCR45 | [9] | CVCL_1416 |
MKN-45 | 女 | 30-33 h | JFCR45 | [10] | CVCL_0434 |
MKN-74 | 男 | 42-46h | JFCR45 | [10] | CVCL_2791 |
卵巢癌
细胞系 | 倍增时间 | 也列入 | 文献 | 外部链接 |
---|---|---|---|---|
OVCAR-3 | 34.7h | NCI-60 | [11] | CVCL_0465 |
OVCAR-4 | 41.4h | NCI-60 | [11] | CVCL_1627 |
OVCAR-5 | 48.8h | NCI-60 | [11] | CVCL_1628 |
OVCAR-8 | 26.1h | NCI-60 | [11] | CVCL_1629 |
SK-OV-3 | 48.7h | NCI-60 | [12] | CVCL_0532 |
结直肠癌
细胞系 | 性别 | 倍增时间 | 也列入 | 文献 | 外部链接 |
---|---|---|---|---|---|
HCC-2998 | 未知 | 31.5h | NCI-60 | [4] | CVCL_1266 |
KM12 | 男 | 23.7h | NCI-60 | [13] | CVCL_1331 |
HT-29 | 女 | 19.5h | NCI-60 | [16] | CVCL_0320 |
HCT 15 | 男 | 20.6h | NCI-60 | [17] | CVCL_0292 |
HCT 116 | 男 | 17.4h | NCI-60 | [18] | CVCL_0291 |
乳腺癌
细胞系 | 类型 | 倍增时间 | 也列入 | 文献 | 外部链接 |
---|---|---|---|---|---|
HBC-4 | ? | ? | JFCR45 | [19] | CVCL_B496 |
BSY-1 | ? | ? | JFCR45 | [19] | CVCL_B499 |
HBC-5 | ? | ? | JFCR45 | [19] | CVCL_B497 |
MCF-7 | HR+ | 25.4h | JFCR45、ICBP43、NCI-60 | [20] | CVCL_0031 |
MDA-MB-231 | 三陰性乳癌 | 41.9h | JFCR45、ICBP43、NCI-60 | [21] | CVCL_0062 |
JFCR45
日本癌研究会后续又设立了细胞系列表JFCR45,包括21种胃癌细胞系,12种肝癌细胞系与12种乳腺癌细胞系[3][27]:
细胞系 | 类型 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|---|
GCIY | 胃腺癌 | 女 | 39Y | [28] | CVCL_1228 |
GT3TKB | 肺鳞状细胞癌 | 男 | 未知 | [3] | CVCL_1237 |
HGC27 | 胃癌 | 未知 | 未知 | [29] | CVCL_1279 |
AZ-521 | 十二指肠腺癌 | 男 | 53Y | [30] | CVCL_2862 |
4-1st | 胃腺癌 | 女 | 51Y | [31] | CVCL_L498 |
NUGC-3 | 胃腺癌 | 72Y | 男 | [32] | CVCL_1612 |
NUGC-3/5-FU | 胃腺癌 | 72Y | 男 | [33] | CVCL_L502 |
HSC-42 | 胃腺癌:横爬型癌 | 未知 | 未知 | [34] | CVCL_0316 |
AGS | 胃腺癌 | 女 | 54Y | [35] | CVCL_0139 |
KWS-1 | 胃腺癌 | 男 | 42Y | [36] | CVCL_9816 |
TSG11 | 胃腺癌 | 女 | 46Y | [3] | CVCL_B477 |
OKIBA | 胃腺癌 | 男 | 52Y | [2] | CVCL_L499 |
ISt-1 | 胃癌 | 男 | 63Y | [37] | CVCL_F645 |
ALF | 胃癌 | 未知 | 未知 | [3] | CVCL_M035 |
AOTO | 胃腺癌 | 男 | 69Y | [2] | CVCL_L501 |
细胞系 | 文献 | 外部链接 |
---|---|---|
Hep G2 | [38] | CVCL_0027 |
Hep 3B | [38] | CVCL_0326 |
Li-7 | [39] | CVCL_3840 |
PLC/PRF/5 | [40] | CVCL_0485 |
Huh7 | [41] | CVCL_0336 |
HLE | [42] | CVCL_1281 |
HLF | [42] | CVCL_2947 |
Huh6 | [43] | CVCL_4381 |
REB | [44] | CVCL_4896 |
SSP-25 | [44] | CVCL_4902 |
HuL-1 | [45] | CVCL_8357 |
JHH-1 | [46] | CVCL_2785 |
细胞系 | 文献 | 外部链接 |
---|---|---|
KPL-3C | [47] | CVCL_E122 |
KPL-4 | [48] | CVCL_5310 |
KPL-1 | [49] | CVCL_2094 |
T-47D | [50] | CVCL_0553 |
HBC-9 | [3] | CVCL_L497 |
ZR-75-1 | [51] | CVCL_0588 |
HBC-8 | [3] | CVCL_L496 |
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