JWH-073

JWH-073，化学名N-正丁基-3-(1-萘甲酰基)吲哚，分子式C23H21NO，属于萘甲酰基吲哚类JWH系列大麻素，是大麻素受体CB1和CB2的全激动剂[2]，由约翰·威廉·霍夫曼小组合成[3]。

JWH-073
法律規範狀態
法律規範
识别
  • Naphthalen-1-yl-(1-butylindol-3-yl)methanone
CAS号208987-48-8  checkY
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.230.192
化学
化学式C23H21NO
摩尔质量327.43 g·mol−1
3D模型（JSmol）
  • CCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43
  • InChI=1S/C23H21NO/c1-2-3-15-24-16-21(19-12-6-7-14-22(19)24)23(25)20-13-8-10-17-9-4-5-11-18(17)20/h4-14,16H,2-3,15H2,1H3 ☒N
  • Key:VCHHHSMPMLNVGS-UHFFFAOYSA-N ☒N

参考文献
  1. . Legal Acts of the Republic of Latvia （Latvian）.
  2. Lisa K. Brents, Anna Gallus-Zawada, Anna Radominska-Pandya, Tamara Vasiljevik, Thomas E Prisinzano, William E Fantegrossi, Jeffery H Moran, Paul L Prather. . Biochemical Pharmacology. 2012, 83 (7): 952–961. PMID 22266354. doi:10.1016/j.bcp.2012.01.004. hdl:1808/22684 可免费查阅. JWH-073 displays equivalent efficacy to that of the CB1R full agonist CP-55,940
  3. Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. . Drug Alcohol Depend. August 2000, 60 (2): 133–40. PMID 10940540. doi:10.1016/S0376-8716(99)00152-0.
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