Diprophylline
Clinical data
Trade namesLufyllin
Other names7-(2,3-Dihydroxy-propyl)theophylline
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa682494
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
  • 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.843
Chemical and physical data
FormulaC10H14N4O4
Molar mass254.246 g·mol−1
3D model (JSmol)
  • O=C2N(c1ncn(c1C(=O)N2C)CC(O)CO)C
  • InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3 checkY
  • Key:KSCFJBIXMNOVSH-UHFFFAOYSA-N checkY
  (verify)

Diprophylline (INN)[1] or dyphylline (USAN) (trade names Dilor, Lufyllin) is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.[2][3]

See also

References

  1. ↑ "International Non-Proprietary Names. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 1" (PDF). World Health Organization. 1955. p. 188.
  2. ↑ Schwabe U, Ukena D, Lohse MJ (September 1985). "Xanthine derivatives as antagonists at A1 and A2 adenosine receptors". Naunyn-Schmiedeberg's Archives of Pharmacology. 330 (3): 212–21. doi:10.1007/bf00572436. PMID 2997628. S2CID 12190457.
  3. ↑ Iancu L, Shneur A, Cohen H (1979). "Trials with xanthine derivatives in systemic treatment of psoriasis". Dermatologica. 159 (1): 55–61. doi:10.1159/000250562. PMID 225216.
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