| GPR52 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | GPR52, G protein-coupled receptor 52 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 604106 MGI: 3643278 HomoloGene: 74561 GeneCards: GPR52 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.[5][6]
Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM][6]
Cannabidiol, CBD, and O-1918 are Inverse agonist at GPR52[7]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000203737 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000118401 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF (Mar 1999). "Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain". Brain Res Mol Brain Res. 64 (2): 193–8. doi:10.1016/S0169-328X(98)00277-0. PMID 9931487.
- 1 2 "Entrez Gene: GPR52 G protein-coupled receptor 52".
- ↑ Stott, Lisa A.; Brighton, Cheryl A.; Brown, Jason; Mould, Richard; Bennett, Kirstie A.; Newman, Robert; Currinn, Heather; Autore, Flavia; Higueruelo, Alicia P.; Tehan, Benjamin G.; MacSweeney, Cliona (2021-06-01). "Characterisation of inverse agonism of the orphan-G protein-coupled receptor GPR52 by cannabinoid ligands Cannabidiol and O-1918". Heliyon. 7 (6): e07201. doi:10.1016/j.heliyon.2021.e07201. ISSN 2405-8440. PMC 8219759. PMID 34189291.
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
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