SSTR1
Identifiers
AliasesSSTR1, SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor 1
External IDsOMIM: 182451 MGI: 98327 HomoloGene: 820 GeneCards: SSTR1
Orthologs
SpeciesHumanMouse
Entrez

6751

20605

Ensembl

ENSG00000139874

ENSMUSG00000035431

UniProt

P30872

P30873

RefSeq (mRNA)

NM_001049

NM_009216

RefSeq (protein)

NP_001040

NP_033242

Location (UCSC)Chr 14: 38.21 – 38.21 MbChr 12: 58.26 – 58.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene.[5][6]

Function

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000139874 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035431 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  6. 1 2 "Entrez Gene: SSTR1 somatostatin receptor 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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