Mucrolysin
Identifiers
EC no.3.4.24.54
CAS no.85898-38-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Zinc metalloproteinase/disintegrin
Identifiers
OrganismProtobothrops mucrosquamatus
Symbol?
UniProtO57413
Search for
StructuresSwiss-model
DomainsInterPro

Mucrolysin (EC 3.4.24.54, Trimeresurus metalloendopeptidase A, mucrotoxin A) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of Ser9-His, His10-Leu, Ala14-Leu, Leu15-Tyr and Tyr16-Leu bonds in insulin B chain

This endopeptidase from the venom of Taiwan habu snake (Protobothrops mucrosquamatus).

References

  1. Sugihara H, Moriura M, Nikai T (1983). "Purification and properties of a lethal, hemorrhagic protein, "mucrotoxin A", from the venom of the Chinese habu snake (Trimeresurus mucrosquamatus)". Toxicon. 21: 247–255. doi:10.1016/0041-0101(83)90009-0. PMID 6857709.
  2. Kishida M, Nikai T, Mori N, Kohmura S, Sugihara H (1985). "Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake)". Toxicon. 23 (4): 637–45. doi:10.1016/0041-0101(85)90368-x. PMID 3904081.
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