OR2K2
Identifiers
AliasesOR2K2, HSHTPCRH06, HTPCRH06, OR2AN1P, OR2AR1P, olfactory receptor family 2 subfamily K member 2
External IDsMGI: 3030101 HomoloGene: 17436 GeneCards: OR2K2
Orthologs
SpeciesHumanMouse
Entrez

26248

258922

Ensembl

ENSG00000171133

ENSMUSG00000043385

UniProt

Q8NGT1

A2AM35

RefSeq (mRNA)

NM_205859

NM_146920

RefSeq (protein)

NP_995581

NP_667131

Location (UCSC)Chr 9: 111.33 – 111.33 MbChr 4: 58.78 – 58.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2K2 is a protein that in humans is encoded by the OR2K2 gene.[5][6][7]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171133 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000043385 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID 1370859. S2CID 43926.
  6. Aloni R, Olender T, Lancet D (Jan 2007). "Ancient genomic architecture for mammalian olfactory receptor clusters". Genome Biol. 7 (10): R88. doi:10.1186/gb-2006-7-10-r88. PMC 1794568. PMID 17010214.
  7. 1 2 "Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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