OR8B8
Identifiers
AliasesOR8B8, TPCR85, olfactory receptor family 8 subfamily B member 8
External IDsMGI: 2177528 HomoloGene: 56568 GeneCards: OR8B8
Orthologs
SpeciesHumanMouse
Entrez

26493

258310

Ensembl

ENSG00000197125

ENSMUSG00000066748

UniProt

Q15620

Q60882

RefSeq (mRNA)

NM_012378

NM_146313

RefSeq (protein)

NP_036510

NP_666425

Location (UCSC)Chr 11: 124.44 – 124.45 MbChr 9: 37.81 – 37.81 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 8B8 is a protein that in humans is encoded by the OR8B8 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000197125 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066748 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
  6. 1 2 "Entrez Gene: OR8B8 olfactory receptor, family 8, subfamily B, member 8".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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