N-(5-硝基-2-吡啶基)乙二胺
N-(5-硝基-2-吡啶基)乙二胺是一种有机化合物，化学式为C7H10N4O2。它可由2-氯-5-硝基吡啶（或2-溴-5-硝基吡啶[1]）和乙二胺在乙腈中反应制得。[2]它和邻苯二甲酸酐在三乙胺存在下于甲苯中回流，可以得到1,2,3,9b-四氢-1-(5-硝基-2-吡啶基)-5H-咪唑并[2,1-a]异吲哚-5-酮。[3]
| N-(5-硝基-2-吡啶基)乙二胺 | |
|---|---|
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| 识别 | |
| CAS号 | 29602-39-9  |
| PubChem | 122425 |
| SMILES |
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| 性质 | |
| 化学式 | C7H10N4O2 |
| 摩尔质量 | 182.18 g·mol−1 |
| 熔点 | 123 °C（396 K） |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献
- Nonpeptide Somatostatin Agonists with sst4 Selectivity: Synthesis and Structure-Activity Relationships of Thioureas. Journal of Medicinal Chemistry (1998), 41(24), 4693-4705. doi:10.1021/jm980118e
- Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3. Journal of Medicinal Chemistry (2017), 60(20), 8482-8514. doi:10.1021/acs.jmedchem.7b00922.
- Cul, Armelle; Daich, Adam; Decroix, Bernard; Sanz, Gerard; Van Hijfte, Luc. . Tetrahedron. 2004. doi:10.1016/j.tet.2004.07.107.
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