SIB-1757
SIB-1757是一种有机化合物,分子式C12H11N3O,带有偶氮基团,可作为代谢型谷氨酸受体亚型mGluR5的受体拮抗剂[1],在动物实验中存在抗痛觉过敏作用[2]。
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CAS号 | 31993-01-8 |
PubChem CID | |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.164.315 |
化学 | |
化学式 | C12H11N3O |
摩尔质量 | 213.24 g·mol−1 |
3D模型(JSmol) | |
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参考文献
- Varney MA, Cosford ND, Jachec C, Rao SP, Sacaan A, Lin FF, Bleicher L, Santori EM, Flor PJ, Allgeier H, Gasparini F, Kuhn R, Hess SD, Veliçelebi G, Johnson EC. . The Journal of Pharmacology and Experimental Therapeutics. July 1999, 290 (1): 170–81. PMID 10381773.
- Dogrul A, Ossipov MH, Lai J, Malan TP, Porreca F. . Neuroscience Letters. October 2000, 292 (2): 115–8. PMID 10998562. doi:10.1016/S0304-3940(00)01458-0.
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