Hexahydrocannabiphorol
Identifiers
  • (6aR,10aR)-6,6,9-trimethyl-3-heptyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Chemical and physical data
FormulaC23H36O2
Molar mass344.539 g·mol−1
3D model (JSmol)
  • CCCCCCCc1cc2OC(C)(C)[C@@H]3CCC(C)C[C@H]3c2c(O)c1

Hexahydrocannabiphorol (HHCP, sometimes mistakenly referred to as hexahydroxycannabiphorol) is a semi-synthetic cannabinoid derivative which has been marketed since around 2021.[1][2] It is believed to be made from the hydrogenation of tetrahydrocannabiphorol (THCP). THCP is only reported as a trace component of cannabis in 2019.[3] HHCP was studied by Roger Adams as early as 1952.[4]

Legality

The legal status of hexahydrocannabinol and derivatives varies between countries leading to widespread sale in some jurisdictions in Europe and the US, but in France HHCP was banned in 2023.[5] Japan banned HHCP on December 26, 2023. Also, HHCP was banned in Slovakia 13.1.2024. [6]

See also

References

  1. ↑ Tanaka R, Kikura-Hanajiri R (June 2023). "Identification of hexahydrocannabinol (HHC), dihydro-iso-tetrahydrocannabinol (dihydro-iso-THC) and hexahydrocannabiphorol (HHCP) in electronic cigarette cartridge products". Forensic Toxicology. doi:10.1007/s11419-023-00667-9. PMID 37365398. S2CID 259259903.
  2. ↑ Höfert L, Becker S, Dreßler J, Baumann S (August 2023). "Quantification of (9R)- and (9S)-hexahydrocannabinol (HHC) via GC-MS in serum/plasma samples from drivers suspected of cannabis consumption and immunological detection of HHC and related substances in serum, urine, and saliva". Drug Testing and Analysis. doi:10.1002/dta.3570. PMID 37652872. S2CID 261430819.
  3. ↑ Hexahydrocannabinol (HHC) and related substances. European Monitoring Centre for Drugs and Drug Addiction, 2023
  4. ↑ https://pubs.acs.org/doi/abs/10.1021/ja01255a061
  5. ↑ "Actualité - L'ANSM classe l'hexahydrocannabinol (HHC) et deux de ses dérivés sur la liste des stupéfiants" [News - The ANSM classifies hexahydrocannabinol (HHC) and two of its derivatives on the list of narcotics]. Agence nationale de sécurité du médicament et des produits de santé (ANSM) (in French). Retrieved 2023-06-12.
  6. ↑ https://english.kyodonews.net/news/2023/12/20893a7e69cb-japan-decides-to-ban-more-cannabinoids-after-gummies-sicken-people.html
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