IL1F10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIL1F10, FIL1-theta, IL-1HY2, IL-38, IL1-theta, IL1HY2, FKSG75, interleukin 1 family member 10 (theta), interleukin 1 family member 10
External IDsOMIM: 615296 MGI: 2652548 HomoloGene: 17690 GeneCards: IL1F10
Orthologs
SpeciesHumanMouse
Entrez

84639

215274

Ensembl

ENSG00000136697

ENSMUSG00000046845

UniProt

Q8WWZ1

Q8R459

RefSeq (mRNA)

NM_173161
NM_032556

NM_153077

RefSeq (protein)

NP_115945
NP_775184

NP_694717

Location (UCSC)Chr 2: 113.07 – 113.08 MbChr 2: 24.18 – 24.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.[5][6][7][8]

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000136697 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046845 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bensen JT, Dawson PA, Mychaleckyj JC, Bowden DW (Dec 2001). "Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14". J Interferon Cytokine Res. 21 (11): 899–904. doi:10.1089/107999001753289505. PMID 11747621.
  6. Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002). "Genomic organization of the interleukin-1 locus". Genomics. 79 (5): 726–33. doi:10.1006/geno.2002.6752. PMID 11991723.
  7. Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002). "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics. 79 (5): 718–25. doi:10.1006/geno.2002.6751. PMID 11991722.
  8. 1 2 "Entrez Gene: IL1F10 interleukin 1 family, member 10 (theta)".

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.