Dicyclohexyl phosphorofluoridate
Names
Other names
DCFP
Dicyclohexyl fluorophosphate
TL-941
T-1840
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C12H22FO3P/c13-17(14,15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h11-12H,1-10H2
    Key: NLPYJEIDHPZCCR-UHFFFAOYSA-N
  • C1CCC(CC1)OP(=O)(OC2CCCCC2)F
Properties
C12H22FO3P
Molar mass 264.277 g·mol−1
Appearance Colorless liquid
Boiling point 116 °C (241 °F; 389 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
Lethal dose or concentration (LD, LC):
110 mg/m3 (inhalation, mice, 10 minutes)
110 mg/m3 (inhalation, rabbits, 10 minutes)
110 mg/m3 (inhalation, rats, 10 minutes)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dicyclohexyl phosphorofluoridate (DCFP),[1] also known as TL-941 or T-1840,[2] is an extremely toxic organophosphorus compound with powerful anticholinesterase action. It's a colorless liquid that is extremely resistant to hydrolysis.[3] DCFP can be produced by reaction of cyclohexanol with phosphoryl dichloride fluoride.[2][3]

See also

References

  1. ↑ BERRY, WK (October 1951). "The turnover number of cholinesterase". Biochemical Journal. 49 (5): 615–20. doi:10.1042/bj0490615. PMC 1197565. PMID 14886354.
  2. 1 2 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
  3. 1 2 Some Aspects Of The Chemistry And Toxic Action Of Organic Compounds Containing Phosphorus And Fluorine. 1957.
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