 | |
| Clinical data | |
|---|---|
| Other names | Echinopsidine Iodide |
| Routes of administration | Oral |
| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number |
|
| PubChem CID | |
| ChemSpider | |
| UNII | |
| Chemical and physical data | |
| Formula | C10H12N2 |
| Molar mass | 160.220 g·mol−1 |
Echinopsidine (Adepren) is an antidepressant that was under development in Bulgaria for the treatment of depression.[1][2] It increases serotonin, norepinephrine, and dopamine levels in the brain and is believed to act as a monoamine oxidase inhibitor (MAOI).[3][4][5] Echinopsidine is found naturally in Echinops echinatus along with the related alkaloids echinopsine and echinozolinone.[6]
See also
References
- ↑ Guliamov MG (1982). "[Experience with the use of new Bulgarian psychotropic drugs]". Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (in Russian). 82 (11): 115–122. PMID 6758442.
- ↑ Guliamov MG (1986). "[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit]". Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (in Russian). 86 (4): 582–587. PMID 3716711.
- ↑ Tiutiulkova N, Gorancheva I (1978). "[Effect of adepren on the cerebral concentration of serotonin]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 17 (2): 83–85. PMID 658004.
- ↑ Stefanova D, Tiutiulkova N, Nikolova M (1976). "[Effect of adepren on the behavior and brain catecholamines of rats in an open field setup]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 15 (1): 42–46. PMID 1269462.
- ↑ Tiutiulkova NI, Gorancheva I (1975). "[Excretion of dopamine, noradrenaline, adrenaline, vanilmandelic acid and 5-hydroxyindoleacetic acid in the urine of volunteers treated with adepren]". Eksperimentalna Meditsina I Morfologiia (in Bulgarian). 14 (4): 187–189. PMID 1222713.
- ↑ Khare CP (2007). "Echinops echinatus Roxb.". Indian Medicinal Plants An Illustrated Dictionary. Springer-Verlag Berlin Heidelberg. ISBN 978-0-387-70637-5.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.