國際癌症研究機構二B類致癌物
2B类致癌物(英語:),為国际癌症研究机构对致癌物质的分类,此类物质(或其混合物)可能对人类致癌。現有236類物質(如黃樟素、四氯化碳、電磁波、抗甲狀腺藥物丙硫氧嘧啶、二異氰酸甲苯、抗愛滋病藥物齐多夫定、汽油引擎廢氣、乾洗業等),對人類為有可能致癌物,對動物為很可能也是致癌物。[1]更多詳細信息,可以搜尋國際癌症研究機構(IARC)專著。[2]
物质和物质组合
中文名稱 | 學名 | CAS号 | 欧盟委员会编号 EINECS |
備考 |
---|---|---|---|---|
A-a-C (2-Amino-9H-pyrido[2,3-b]indole) | US Biological 化學試藥類 | |||
乙醛 | Acetaldehyde | 0 | ||
乙酰胺 | Acetamide | 0 | ||
Acétate de médroxyprogestérone | 0 | |||
Acétate de méthylazoxyméthanol | 0 | |||
乙酸乙烯酯 | Acétate de vinyle | 0 | ||
咖啡酸 | Acide caféique | 0 | ||
Acide chlorendique | 0 | |||
二氯乙酸 | 0 | |||
氨三乙酸 | 0 | |||
Acrylate d'éthyle | 0 | |||
丙烯腈 | Acrylonitrile | 0 | ||
阿达帕林 | Adapalene | |||
AF-2 | Furylfuramide |
硝基蚨喃類殺菌劑,結構類似对羟基苯甲酸酯 | ||
黃麴毒素 M1 | Aflatoxin,M1 | 2 | ||
對-氨基偶氮苯 | Aniline Yellow para-Aminoazobenzene |
0 | 苯胺黃 | |
鄰-氨基偶氮甲苯 | ortho-Aminoazotoluene | 0 | 蘇丹紅IV代謝生成的物質 | |
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | 1 | |||
胺苯吖啶 | Amsacrine | 5 | 抗腫瘤藥,別名安丫啶、安吖啶 | |
鄰氨基苯甲醚 | ortho-Anisidine | 0 | ||
三氧化二锑 | Antimony trioxide | 1 | ||
異黃樟 | Aramite | 別名殺螨特;異黃樟;殺螨劑 | ||
金胺O | Auramine | 0 | 工業級(technical-grade) | |
重氮乙酰絲氨酸 | Azaserine | 0 | 別名氮絲氨酸;氮雜絲氨酸;重氮絲氨酸 - 用以抑制某些腫瘤生長的抗生素 | |
氮丙环 | Aziridine | 0 | ||
Benz[j]aceanthrylene | (多環芳香烴,PAHs) | |||
Benz(''a'')anthracene | 0 | (多環芳香烴,PAHs) | ||
Benzo(b)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(j)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(k)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(''c'')phenanthrene | 0 | (多環芳香烴,PAHs) | ||
苯并呋喃 | 、 | 0 | (多環芳香烴,PAHs) | |
Benzyl violet 4B 酸性紫4B |
紫色1號,C39H40N3NaO6S2,3-[[Ethyl[4-[[4-(dimethyliminio)-2,5-cyclohexadiene-1-ylidene][4-[ethyl[3-(sodiooxysulfonyl)benzyl]amino]phenyl]methyl]phenyl]amino]methyl]benzenesulfonate | 1 | 主要用于羊毛、丝绸、锦纶的染色[3] | |
二溴新戊醇 2,2-雙(溴甲基)-1,3-丙二醇 |
2,2-Bis(bromomethyl)propane-1,3-diol | 2 | 中間體或阻燃劑[4][5] | |
博来霉素 | Bleomycin | |||
Bracken fern | ;[6][7][8] | |||
溴二氯甲烷 | Bromodichloromethane | 0 | ||
丁基羟基茴香醚 | Butylated hydroxyanisole | 4 | ||
β-丁內酯 | b-Butyrolactone,别名4-甲基-β-丙酰内酯;B-丁内酯;Β-丁内酮,分子式为C4H6O2 | 2 | 酯類,可作單體[9][10] | |
碳煙 | Carbon black | |||
四氯化碳 | Carbon tetrachloride | |||
邻苯二酚 | Catechol | |||
氯丹 | Chlordane | |||
十氯酮 | (開蓬,殺蟲﹑殺真菌藥,原商標名) | |||
氯菌酸 | 六氯內-甲烯基-四氫苯二甲酸 | 毒性「氣喘、肺水腫、過敏性皮膚炎、灼熱疼痛感,視線模糊並流淚」 | ||
4-氯苯胺 | para-Chloroaniline | 0 | ||
- 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
- 氯仿
- 1-Chloro-2-methylpropene
- Chlorophenoxy herbicides
- 4-Chloro-ortho-phenylenediamine
- 氯丁二烯
- 百菌清
- 䓛
- CI Acid Red 114
- 副玫瑰苯胺
- CI Direct Blue 15
- Citrus Red 2
- 钴以及钴化合物
- Cobalt sulfate and other soluble cobalt(II) salts
- Cocamide DEA condensate
- para-Cresidine
- Cycasin
- 达卡巴嗪
- 丹蒽醌 (Chrysazin, 1,8-Dihydroxyanthraquinone)
- 道諾黴素
- 滴滴涕 (p,p'-DDT)
- N,N'-Diacetylbenzidine
- 2,4-Diaminoanisole
- 4,4'-二氨基二苯醚
- 2,4-Diaminotoluene
- Dibenz[a,h]acridine
- Dibenz[a,j]acridine
- 7H-Dibenzo[c,g]carbazole
- Dibenzo[a,e]pyrene
- Dibenzo[a,h]pyrene
- Dibenzo[a,i]pyrene
- 1,2-二溴-3-氯丙烷
- 2,3-Dibromopropan-1-ol
- 二氯乙酸
- 对二氯苯
- 3,3'-Dichlorobenzidine
- 3,3'-Dichloro-4,4'-diaminodiphenyl ether
- 1,2-二氯乙烷
- 二氯甲烷 (methylene chloride)
- 1,3-Dichloropropene (technical grade)
- 敌敌畏
- 1,2-Diethylhydrazine
- Diglycidyl resorcinol ether
- Dihydrosafrole
- Diisopropyl sulfate
- 3,3'-Dimethoxybenzidine (o-Dianisidine)
- 甲基黄
- trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
- 2,6-Xylidine (2,6-Dimethylaniline)
- 3,3'-Dimethylbenzidine (o-Tolidine)
- 偏二甲肼
- 3,7-Dinitrofluoranthene
- 3,9-Dinitrofluoranthene
- 1,6-Dinitropyrene
- 1,8-Dinitropyrene
- 2,4-二硝基甲苯
- 二硝基甲苯
- 1,4-二噁烷
- Disperse Blue 1
- 1,2-环氧丁烷
- 丙烯酸乙酯
- 乙苯
- 1,2-二氯乙烷
- 甲磺酸乙酯
- Foreign bodies, implanted in tissues
- Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))
- Metallic, prepared as thin smooth films
- Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron
- 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
- Fumonisin B1
- 呋喃
- Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole)
- Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
- Glycidaldehyde
- 灰黃黴素
- HC Blue No. 1
- 七氯
- 六氯苯
- 六氯乙烷
- 六氯环己烷s
- 六甲基磷酰胺 (HMPA)
- 人類免疫缺陷病毒 type 2 (infection with)
- 人類乳突病毒es: some types other than 16, 18, 31 and 33
- 聯氨
- 1-Hydroxyanthraquinone
- Indeno[1,2,3-cd]pyrene
- Iron-dextran complex
- 異戊二烯
- Lasiocarpine
- Lead
- 磁場s (極低頻)
- MeA-a-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
- Medroxyprogesterone acetate
- MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
- MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
- Merphalan
- 丙烯亚胺 (Propyleneimine)
- Methylazoxymethanol acetate
- 5-Methylchrysene
- 4,4'-Methylene bis(2-methylaniline)
- 4,4'-Methylenedianiline
- Methylmercury compounds
- 2-Methyl-1-nitroanthraquinone (uncertain purity)
- N-Methyl-N-nitrosourethane
- Methylthiouracil
- 甲硝唑
- Michler's base (4,4'-methylene-bis(N,N-dimethyl)benzenamine)
- 米氏酮 (4,4'-bis(dimethylamino)benzophenone)
- Microcystin-LR
- 滅蟻樂
- 丝裂霉素C
- 米托蒽醌
- Monocrotaline
- 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- Nafenopin
- 萘
- 镍, metallic and alloys
- Niridazole
- 氨三乙酸 and its salts
- 5-Nitroacenaphthene
- 2-Nitroanisole
- 硝基苯
- 6-Nitrochrysene
- 護谷 (technical-grade)
- 2-Nitrofluorene
- 1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
- N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
- Nitrogen mustard N-oxide
- 硝基甲烷
- 2-硝基丙烷
- 1-硝基芘
- 4-Nitropyrene
- N-Nitrosodi-n-butylamine
- N-Nitrosodiethanolamine
- N-Nitrosodi-n-propylamine
- 3-(N-Nitrosomethylamino)propionitrile
- N-Nitrosomethylethylamine
- N-Nitrosomethylvinylamine
- N-Nitrosomorpholine
- N-Nitrosopiperidine
- N-Nitrosopyrrolidine
- N-Nitrososarcosine
- Ochratoxin A
- Oestrogen-progestogen therapy, postmenopausal
- Oil Orange SS
- 奥沙西泮
- 坡缕石 (attapulgite) (long fibres, >5微米)
- Panfuran S (containing dihydroxymethylfuratrizine)
- 非那吡啶
- 苯巴比妥
- 酚酞
- Phenoxybenzamine hydrochloride
- Phenyl glycidyl ether
- 苯妥英
- PhIP (2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine)
- Polychlorophenols and their sodium salts (mixed exposures)
- Ponceau MX
- Ponceau 3R
- 溴酸钾
- Progestins
- Progestogen-only contraceptives
- 1,3-丙磺酸内酯
- Β-丙內酯
- 环氧丙烷
- (Propylthiouracil、PTU),抗甲狀腺藥物[11]
- 无线电波, such as, but not limited to, those associated with 移动电话 [12]
- Refractory ceramic fibres
- Riddelliine
- 黃樟素Safrole
- 日本血吸虫 (infection with)
- Sodium orthophenyl phenol
- Special-purpose fibres such as E-glass and '475' glass fibres
- Sterigmatocystin
- 链脲佐菌素
- 苯乙烯
- Sulfallate
- 四氟乙烯
- 四硝基甲烷
- 硫乙醯胺
- 4,4'-Thiodianiline
- Thiouracil
- 二氧化鈦
- 二異氰酸甲苯(2,4-Toluene diiso-cyanate, 2,4-TDI)[13][14][15]
- Trichlormethine (Trimustine hydrochloride)
- Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
- Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
- 台盼蓝
- Uracil mustard
- 五氧化二钒
- 乙酸乙烯酯
- 4-乙烯基环己烯
- 4-Vinylcyclohexene diepoxide
- Zalcitabine
- 齐多夫定(Zidovudine,AZT)
- 阿斯巴甜[16]
注释
- 脚注
引用
- 談環境中的致癌物 (页面存档备份,存于) - 台北榮民總醫院 毒物科 楊振昌醫師
- preamble to the IARC Monographs (页面存档备份,存于)pdf
- . [2014-11-24]. (原始内容存档于2020-02-03).
- (PDF). [2014-11-24]. (原始内容存档 (PDF)于2014-11-29).
- Bracken Fern - Bracken Fern or Brake Fern (Pteridium aquilinum) - Plants toxic to animals (页面存档备份,存于) - Veterinary Medicine library at U of Illinois
- . [2014-11-24]. (原始内容存档于2019-07-28).
- (PDF). [2014-11-24]. (原始内容存档 (PDF)于2016-03-03).
- . [2014-09-20]. (原始内容存档于2020-02-03).
- 物質安全資料表 (页面存档备份,存于) - 勞動部勞動及職業安全衛生研究所
- . [2014-11-24]. (原始内容存档于2014-11-18).
- Press release No 208, 31 May 2011 (页面存档备份,存于), IARC classifies Radiofrequency Electromagnetic Fields as possibly carcinogenic to humans
- 二異氰酸甲苯 (页面存档备份,存于) - 行政院毒災防救管理資訊系統
- 2,4-二異氰酸甲苯健康危害 (页面存档备份,存于) - 國立陽明大學環境衛生研究所
- 中華民國七十六年一月十五日,台北縣某工廠因二異氰酸甲苯(Toluene diisocyanate , TDI) (页面存档备份,存于) - 衛生福利部疾病管制署
- . 联合国新闻. 2023-07-13 [2023-07-14] (中文).
- J, Wilbourn; C, Partensky; WG., Morgan. . International Agency for Research on Cancer. 1996 [2023-10-31]. PMID 9148039. (原始内容存档于2022-12-22).
- . IARC Publications Website. [2023-10-31]. (原始内容存档于2023-10-31).
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