Forkhead box protein F1 (FOXF1) is a protein that in humans is encoded by the FOXF1 gene.[5][6][7]
Function
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOX1 protein is important in the development of the pulmonary mesenchyme and the development of the gastrointestinal tract.[8]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000103241 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042812 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Larsson C, Hellqvist M, Pierrou S, White I, Enerbäck S, Carlsson P (Dec 1995). "Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12)". Genomics. 30 (3): 464–9. doi:10.1006/geno.1995.1266. PMID 8825632.
- ↑ Pierrou S, Hellqvist M, Samuelsson L, Enerbäck S, Carlsson P (Oct 1994). "Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending". The EMBO Journal. 13 (20): 5002–12. doi:10.1002/j.1460-2075.1994.tb06827.x. PMC 395442. PMID 7957066.
- ↑ "Entrez Gene: FOXF1 forkhead box F1".
- ↑ "FOXF1 gene: MedlinePlus Genetics". medlineplus.gov. Retrieved 2021-06-10.
Further reading
- Murphy DB, Wiese S, Burfeind P, Schmundt D, Mattei MG, Schulz-Schaeffer W, Thies U (Jun 1994). "Human brain factor 1, a new member of the fork head gene family". Genomics. 21 (3): 551–7. doi:10.1006/geno.1994.1313. PMID 7959731.
- Hellqvist M, Mahlapuu M, Samuelsson L, Enerbäck S, Carlsson P (Feb 1996). "Differential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2". The Journal of Biological Chemistry. 271 (8): 4482–90. doi:10.1074/jbc.271.8.4482. PMID 8626802.
- Hellqvist M, Mahlapuu M, Blixt A, Enerbäck S, Carlsson P (Sep 1998). "The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB". The Journal of Biological Chemistry. 273 (36): 23335–43. doi:10.1074/jbc.273.36.23335. PMID 9722567.
- Mahlapuu M, Pelto-Huikko M, Aitola M, Enerbäck S, Carlsson P (Oct 1998). "FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfaces". Developmental Biology. 202 (2): 183–95. doi:10.1006/dbio.1998.9010. PMID 9769171.
- Coon DR, Roberts DJ, Loscertales M, Kradin R (Apr 2006). "Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia". Experimental and Molecular Pathology. 80 (2): 119–23. doi:10.1016/j.yexmp.2005.12.003. PMID 16448649.
- Lomenick JP, Hubert MA, Handwerger S (Nov 2006). "Transcription factor FOXF1 regulates growth hormone variant gene expression". American Journal of Physiology. Endocrinology and Metabolism. 291 (5): E947-51. doi:10.1152/ajpendo.00128.2006. PMID 16772323.
External links
- FOXF1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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