HMGN4
Identifiers
AliasesHMGN4, HMG17L3, NHC, high mobility group nucleosomal binding domain 4
External IDsHomoloGene: 105484 GeneCards: HMGN4
Orthologs
SpeciesHumanMouse
Entrez

10473

n/a

Ensembl

ENSG00000182952

n/a

UniProt

O00479

n/a

RefSeq (mRNA)

NM_006353

n/a

RefSeq (protein)

NP_006344
NP_006344.1

n/a

Location (UCSC)Chr 6: 26.54 – 26.55 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

High mobility group nucleosome-binding domain-containing protein 4 is a transcription factor that in humans is encoded by the HMGN4 gene.[3][4]

Function

The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene.[3]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000182952 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. 1 2 "Entrez Gene: high mobility group nucleosomal binding domain 4".
  4. Birger Y, Ito Y, West KL, Landsman D, Bustin M (May 2001). "HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene". DNA Cell Biol. 20 (5): 257–64. doi:10.1089/104454901750232454. PMID 11410162.

Further reading


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