| LYL1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | LYL1, bHLHa18, lymphoblastic leukemia associated hematopoiesis regulator 1, basic helix-loop-helix family member, LYL1 basic helix-loop-helix family member | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 151440 MGI: 96891 HomoloGene: 4078 GeneCards: LYL1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.[5][6]
Interactions
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000104903 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034041 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Mellentin JD, Smith SD, Cleary ML (July 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. doi:10.1016/0092-8674(89)90404-2. PMID 2752424. S2CID 24737263.
- ↑ "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".
- ↑ Miyamoto A, Cui X, Naumovski L, Cleary ML (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Molecular and Cellular Biology. 16 (5): 2394–401. doi:10.1128/mcb.16.5.2394. PMC 231228. PMID 8628307.
- ↑ Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D (January 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. 18 (4): 995–1005. doi:10.1038/sj.onc.1202374. PMID 10023675.
Further reading
- Xia Y, Brown L, Yang CY, Tsan JT, Siciliano MJ, Espinosa R, Le Beau MM, Baer RJ (December 1991). "TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia". Proceedings of the National Academy of Sciences of the United States of America. 88 (24): 11416–20. Bibcode:1991PNAS...8811416X. doi:10.1073/pnas.88.24.11416. PMC 53146. PMID 1763056.
- Kuo SS, Mellentin JD, Copeland NG, Gilbert DJ, Jenkins NA, Cleary ML (June 1991). "Structure, chromosome mapping, and expression of the mouse Lyl-1 gene". Oncogene. 6 (6): 961–8. PMID 2067848.
- Saltman DL, Mellentin JD, Smith SD, Cleary ML (November 1990). "Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization". Genes, Chromosomes & Cancer. 2 (4): 259–65. doi:10.1002/gcc.2870020402. PMID 2268576. S2CID 103922.
- Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R (October 1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". The EMBO Journal. 13 (20): 4831–9. doi:10.1002/j.1460-2075.1994.tb06809.x. PMC 395422. PMID 7957052.
- Trask B, Fertitta A, Christensen M, Youngblom J, Bergmann A, Copeland A, de Jong P, Mohrenweiser H, Olsen A, Carrano A (January 1993). "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers". Genomics. 15 (1): 133–45. doi:10.1006/geno.1993.1021. PMID 8432525.
- Miyamoto A, Cui X, Naumovski L, Cleary ML (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Molecular and Cellular Biology. 16 (5): 2394–401. doi:10.1128/mcb.16.5.2394. PMC 231228. PMID 8628307.
- Mahajan MA, Park ST, Sun XH (June 1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins". Oncogene. 12 (11): 2343–50. PMID 8649774.
- Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D (January 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. 18 (4): 995–1005. doi:10.1038/sj.onc.1202374. PMID 10023675.
- Meng YS, Khoury H, Dick JE, Minden MD (November 2005). "Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia". Leukemia. 19 (11): 1941–7. doi:10.1038/sj.leu.2403836. PMID 16094422.
External links
- LYL1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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