Consisting of about 110 amino acids, the domain in winged-helix transcription factors (see Regulation of gene expression) has four helices and a two-strand beta-sheet.
These proteins are classified into 19 families called FoxA-FoxS.
Mutations in FoxP proteins are implicated in human autoimmune diseases.
See also
External links
- Winged-Helix+Transcription+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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see also transcription factor/coregulator deficiencies | |||||||||||||||||||||||||||||||
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